Matches in SemOpenAlex for { <https://semopenalex.org/work/W3137858222> ?p ?o ?g. }
- W3137858222 endingPage "330" @default.
- W3137858222 startingPage "319" @default.
- W3137858222 abstract "Diabetes mellitus is a global health problem, and its prevalence continues to increase. Dietary supplements, including probiotics, prebiotics, and plant extracts, have been shown to alleviate diabetes. In this study, the synergistic effects of two types of dietary supplements were investigated in a mouse model of type 2 diabetes mellitus (T2DM). Sixty mice were divided into the following six groups: control, model (induced by a high-fat diet and intraperitoneal injection of streptozotocin), drug (metformin), probiotic (Lactobacillus spp.), formula A (probiotics, plant extracts, and soybean peptide), and formula B (probiotics, prebiotics, and soybean peptide). All three dietary interventions (probiotic, formula A, and formula B groups) significantly reduced the blood glucose level and oral glucose tolerance level and effectively improved some biochemical parameters (e.g., chronic inflammation, oxidative stress, and blood lipid level) and regulated gut microbiota. Notably, formula B exhibited a better ability on reducing the blood glucose level, regulating the gut microbiota, and increasing the short-chain fatty acid levels compared with the probiotics alone and formula A. Thus, formula B may exert synergistic protective effects against T2DM through a mechanism involving probiotics and prebiotics of gut microbiota regulation. This study provides a theoretical basis for the application of probiotic dietary supplements to the treatment of T2DM." @default.
- W3137858222 created "2021-03-29" @default.
- W3137858222 creator A5019394845 @default.
- W3137858222 creator A5027181959 @default.
- W3137858222 creator A5028222768 @default.
- W3137858222 creator A5035534812 @default.
- W3137858222 creator A5039563629 @default.
- W3137858222 creator A5040558103 @default.
- W3137858222 creator A5045846608 @default.
- W3137858222 creator A5049341927 @default.
- W3137858222 creator A5069260620 @default.
- W3137858222 creator A5084574430 @default.
- W3137858222 date "2021-03-01" @default.
- W3137858222 modified "2023-10-18" @default.
- W3137858222 title "Synergistic Protective Effects of Different Dietary Supplements Against Type 2 Diabetes via Regulating Gut Microbiota" @default.
- W3137858222 cites W1508496854 @default.
- W3137858222 cites W1969112284 @default.
- W3137858222 cites W1970170253 @default.
- W3137858222 cites W1972828030 @default.
- W3137858222 cites W1973058491 @default.
- W3137858222 cites W2006208547 @default.
- W3137858222 cites W2024352719 @default.
- W3137858222 cites W2033395930 @default.
- W3137858222 cites W2044224865 @default.
- W3137858222 cites W2046558305 @default.
- W3137858222 cites W2048910697 @default.
- W3137858222 cites W2058987765 @default.
- W3137858222 cites W2071841602 @default.
- W3137858222 cites W2085265179 @default.
- W3137858222 cites W2093765481 @default.
- W3137858222 cites W2098702370 @default.
- W3137858222 cites W2101209169 @default.
- W3137858222 cites W2123349844 @default.
- W3137858222 cites W2128526406 @default.
- W3137858222 cites W2141452792 @default.
- W3137858222 cites W2151476184 @default.
- W3137858222 cites W2156632881 @default.
- W3137858222 cites W2164916046 @default.
- W3137858222 cites W2171016495 @default.
- W3137858222 cites W2198746073 @default.
- W3137858222 cites W2290110623 @default.
- W3137858222 cites W2296954214 @default.
- W3137858222 cites W2347036634 @default.
- W3137858222 cites W2461853012 @default.
- W3137858222 cites W2471638204 @default.
- W3137858222 cites W2508121172 @default.
- W3137858222 cites W2519916383 @default.
- W3137858222 cites W2549568832 @default.
- W3137858222 cites W2604894279 @default.
- W3137858222 cites W2766150630 @default.
- W3137858222 cites W2770854107 @default.
- W3137858222 cites W2783754831 @default.
- W3137858222 cites W2791886727 @default.
- W3137858222 cites W2793130698 @default.
- W3137858222 cites W2795638059 @default.
- W3137858222 cites W2892059936 @default.
- W3137858222 cites W2946981492 @default.
- W3137858222 cites W2955331731 @default.
- W3137858222 cites W2966218572 @default.
- W3137858222 cites W3004722943 @default.
- W3137858222 cites W3028379346 @default.
- W3137858222 cites W4312760520 @default.
- W3137858222 doi "https://doi.org/10.1089/jmf.2020.4759" @default.
- W3137858222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33739885" @default.
- W3137858222 hasPublicationYear "2021" @default.
- W3137858222 type Work @default.
- W3137858222 sameAs 3137858222 @default.
- W3137858222 citedByCount "6" @default.
- W3137858222 countsByYear W31378582222021 @default.
- W3137858222 countsByYear W31378582222022 @default.
- W3137858222 countsByYear W31378582222023 @default.
- W3137858222 crossrefType "journal-article" @default.
- W3137858222 hasAuthorship W3137858222A5019394845 @default.
- W3137858222 hasAuthorship W3137858222A5027181959 @default.
- W3137858222 hasAuthorship W3137858222A5028222768 @default.
- W3137858222 hasAuthorship W3137858222A5035534812 @default.
- W3137858222 hasAuthorship W3137858222A5039563629 @default.
- W3137858222 hasAuthorship W3137858222A5040558103 @default.
- W3137858222 hasAuthorship W3137858222A5045846608 @default.
- W3137858222 hasAuthorship W3137858222A5049341927 @default.
- W3137858222 hasAuthorship W3137858222A5069260620 @default.
- W3137858222 hasAuthorship W3137858222A5084574430 @default.
- W3137858222 hasConcept C134018914 @default.
- W3137858222 hasConcept C203014093 @default.
- W3137858222 hasConcept C2777180221 @default.
- W3137858222 hasConcept C31903555 @default.
- W3137858222 hasConcept C539455810 @default.
- W3137858222 hasConcept C555293320 @default.
- W3137858222 hasConcept C71924100 @default.
- W3137858222 hasConcept C86803240 @default.
- W3137858222 hasConceptScore W3137858222C134018914 @default.
- W3137858222 hasConceptScore W3137858222C203014093 @default.
- W3137858222 hasConceptScore W3137858222C2777180221 @default.
- W3137858222 hasConceptScore W3137858222C31903555 @default.
- W3137858222 hasConceptScore W3137858222C539455810 @default.
- W3137858222 hasConceptScore W3137858222C555293320 @default.
- W3137858222 hasConceptScore W3137858222C71924100 @default.
- W3137858222 hasConceptScore W3137858222C86803240 @default.