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- W3137883384 abstract "Abstract Nucleotide composition (GC content) varies across bacteria species, genome regions, and specific genes. In Xylella fastidiosa, a vector-borne fastidious plant pathogen infecting multiple crops, GC content ranges between ∼51-52%; however, these values were gathered using limited genomic data. We evaluated GC content variations across X. fastidiosa subspecies fastidiosa (N = 194), subsp. pauca (N = 107), and subsp. multiplex (N = 39). Genomes were classified based on plant host and geographic origin; individual genes within each genome were classified based on gene function, strand, length, ortholog group, core vs accessory, and recombinant vs non-recombinant. GC content was calculated for each gene within each evaluated genome. The effects of genome and gene-level variables were evaluated with a mixed effect ANOVA, and the marginal-GC content was calculated for each gene. Also, the correlation between gene-specific GC content vs natural selection (dN/dS) and recombination/mutation (r/m) was estimated. Our analyses show that intra-genomic changes in nucleotide composition in X. fastidiosa are small and influenced by multiple variables. Higher AT-richness is observed in genes involved in replication and translation, and genes in the leading strand. In addition, we observed a negative correlation between high-AT and dN/dS in subsp. pauca. The relationship between recombination and GC content varied between core and accessory genes. We hypothesize that distinct evolutionary forces and energetic constraints both drive and limit these small variations in nucleotide composition." @default.
- W3137883384 created "2021-03-29" @default.
- W3137883384 creator A5027734252 @default.
- W3137883384 creator A5071564558 @default.
- W3137883384 date "2021-03-14" @default.
- W3137883384 modified "2023-09-23" @default.
- W3137883384 title "Evidence of gene nucleotide composition favoring replication and growth in a fastidious plant pathogen" @default.
- W3137883384 cites W1573821798 @default.
- W3137883384 cites W1730105450 @default.
- W3137883384 cites W1747983814 @default.
- W3137883384 cites W1822482735 @default.
- W3137883384 cites W1915578613 @default.
- W3137883384 cites W1948404504 @default.
- W3137883384 cites W1968121337 @default.
- W3137883384 cites W1985818080 @default.
- W3137883384 cites W1988590400 @default.
- W3137883384 cites W1995548425 @default.
- W3137883384 cites W2001852290 @default.
- W3137883384 cites W2002829084 @default.
- W3137883384 cites W2007332307 @default.
- W3137883384 cites W2012246701 @default.
- W3137883384 cites W2016588572 @default.
- W3137883384 cites W2017205981 @default.
- W3137883384 cites W2017689629 @default.
- W3137883384 cites W2025021478 @default.
- W3137883384 cites W2027653803 @default.
- W3137883384 cites W2030243652 @default.
- W3137883384 cites W2031959919 @default.
- W3137883384 cites W2033095314 @default.
- W3137883384 cites W2036506053 @default.
- W3137883384 cites W2040351382 @default.
- W3137883384 cites W2043926219 @default.
- W3137883384 cites W2044044562 @default.
- W3137883384 cites W2052903982 @default.
- W3137883384 cites W2058947330 @default.
- W3137883384 cites W2062154277 @default.
- W3137883384 cites W2062525446 @default.
- W3137883384 cites W2071506236 @default.
- W3137883384 cites W2074456979 @default.
- W3137883384 cites W2076219800 @default.
- W3137883384 cites W2077319392 @default.
- W3137883384 cites W2080938078 @default.
- W3137883384 cites W2088819045 @default.
- W3137883384 cites W2092604303 @default.
- W3137883384 cites W2095002940 @default.
- W3137883384 cites W2096093282 @default.
- W3137883384 cites W2096375646 @default.
- W3137883384 cites W2098502612 @default.
- W3137883384 cites W2098567697 @default.
- W3137883384 cites W2102619694 @default.
- W3137883384 cites W2105360874 @default.
- W3137883384 cites W2108234281 @default.
- W3137883384 cites W2108421367 @default.
- W3137883384 cites W2109326924 @default.
- W3137883384 cites W2115622704 @default.
- W3137883384 cites W2115672772 @default.
- W3137883384 cites W2116279310 @default.
- W3137883384 cites W2120902911 @default.
- W3137883384 cites W2122673596 @default.
- W3137883384 cites W2123516016 @default.
- W3137883384 cites W2124165778 @default.
- W3137883384 cites W2125882863 @default.
- W3137883384 cites W2126627383 @default.
- W3137883384 cites W2131224273 @default.
- W3137883384 cites W2131998787 @default.
- W3137883384 cites W2133790733 @default.
- W3137883384 cites W2135999147 @default.
- W3137883384 cites W2137119243 @default.
- W3137883384 cites W2138178197 @default.
- W3137883384 cites W2141052558 @default.
- W3137883384 cites W2148639963 @default.
- W3137883384 cites W2150570211 @default.
- W3137883384 cites W2150846476 @default.
- W3137883384 cites W2151102421 @default.
- W3137883384 cites W2155090350 @default.
- W3137883384 cites W2155313208 @default.
- W3137883384 cites W2155734003 @default.
- W3137883384 cites W2157913328 @default.
- W3137883384 cites W2164367233 @default.
- W3137883384 cites W2165206297 @default.
- W3137883384 cites W2165696271 @default.
- W3137883384 cites W2165924016 @default.
- W3137883384 cites W2169812063 @default.
- W3137883384 cites W2170551349 @default.
- W3137883384 cites W2175799720 @default.
- W3137883384 cites W2227578447 @default.
- W3137883384 cites W2267600754 @default.
- W3137883384 cites W2432815617 @default.
- W3137883384 cites W2460939791 @default.
- W3137883384 cites W2534760794 @default.
- W3137883384 cites W2549973881 @default.
- W3137883384 cites W2566910084 @default.
- W3137883384 cites W2579493271 @default.
- W3137883384 cites W2585822716 @default.
- W3137883384 cites W2586669868 @default.
- W3137883384 cites W2588280889 @default.
- W3137883384 cites W2588835098 @default.
- W3137883384 cites W2605530157 @default.
- W3137883384 cites W2609196796 @default.
- W3137883384 cites W2611251675 @default.