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- W3138335087 abstract "This chapter focuses on recent advances in the definition, pathogenesis, assessment tools, and clinical implications of physical frailty in the setting of liver transplantation. Physical frailty is the component that has most frequently been described in end-stage liver disease (ESLD), but there remains a lack of consensus regarding the definition in this patient population. ESLD is characterized by marked fluctuations in liver disease severity and dramatic responses to therapeutic interventions, all of which likely contribute to worsening frailty. The causes of physical frailty in ESLD are multifactorial. The liver-related factors revolve around a state of severe protein catabolism, malnutrition, chronic inflammatory state, endocrine dysfunction, and barriers to physical activity. The chapter summarizes the measurement tools used to assess physical frailty. It also summarizes the components of sarcopenia, physical function, functional independence, and aerobic exercise capacity." @default.
- W3138335087 created "2021-03-29" @default.
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- W3138335087 date "2021-03-12" @default.
- W3138335087 modified "2023-09-24" @default.
- W3138335087 title "Frailty and the Potential Liver Transplant Candidate" @default.
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- W3138335087 doi "https://doi.org/10.1002/9781119634010.ch4" @default.
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