FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3138550658> ?p ?o ?g. }

• W3138550658 endingPage "e16846" @default.
• W3138550658 startingPage "e16846" @default.
• W3138550658 abstract "Older patients account for a significant proportion of patients undergoing colorectal cancer surgery and are vulnerable to a number of preoperative risk factors that are not often present in younger patients. Further, three preoperative risk factors that are more prevalent in older adults include frailty, sarcopenia, and malnutrition. Although each of these has been studied in isolation, there is little information on the interplay between them in older surgical patients. A particular area of increasing interest is the use of urine metabolomics for the objective evaluation of dietary profiles and malnutrition.Herein, we describe the design, cohort, and standard operating procedures of a planned prospective study of older surgical patients undergoing colorectal cancer resection across multiple institutions in the United Kingdom. The objectives are to determine the association between clinical outcomes and frailty, nutritional status, and sarcopenia.The procedures will include serial frailty evaluations (Clinical Frailty Scale and Groningen Frailty Indicator), functional assessments (hand grip strength and 4-meter walk test), muscle mass evaluations via computerized tomography morphometric analysis, and the evaluation of nutritional status via the analysis of urinary dietary biomarkers. The primary feasibility outcome is the estimation of the incidence rate of postoperative complications, and the primary clinical outcome is the association between the presence of postoperative complications and frailty, sarcopenia, and nutritional status. The secondary outcome measures are the length of hospital stay, 30-day hospital readmission rate, and mortality rate at days 30 and 90.Our study was approved by the National Health Service Research Ethics Committee (reference number: 19/WA/0190) via the Integrated Research Application System (project ID: 231694) prior to subject recruitment. Cardiff University is acting as the study sponsor. Our study is financially supported through an external, peer-reviewed grant from the British Geriatrics Society and internal funding resources from Cardiff University. The results will be disseminated through peer-review publications, social media, and conference proceedings.As frailty, sarcopenia, and malnutrition are all areas of common derangement in the older surgical population, prospectively studying these risk factors in concert will allow for the analysis of their interplay as well as the development of predictive models for those at risk of commonly tracked surgical complications and outcomes.PRR1-10.2196/16846." @default.
• W3138550658 created "2021-03-29" @default.
• W3138550658 creator A5001488716 @default.
• W3138550658 creator A5007761449 @default.
• W3138550658 creator A5015888087 @default.
• W3138550658 creator A5021781781 @default.
• W3138550658 creator A5043285442 @default.
• W3138550658 creator A5046465972 @default.
• W3138550658 creator A5062037948 @default.
• W3138550658 creator A5069669005 @default.
• W3138550658 creator A5072331751 @default.
• W3138550658 creator A5087877314 @default.
• W3138550658 creator A5090126800 @default.
• W3138550658 date "2021-08-17" @default.
• W3138550658 modified "2023-10-01" @default.
• W3138550658 title "Association of Postoperative Clinical Outcomes With Sarcopenia, Frailty, and Nutritional Status in Older Patients With Colorectal Cancer: Protocol for a Prospective Cohort Study" @default.
• W3138550658 cites W1517324007 @default.
• W3138550658 cites W2008533112 @default.
• W3138550658 cites W2028626540 @default.
• W3138550658 cites W2033839954 @default.
• W3138550658 cites W2095439262 @default.
• W3138550658 cites W2096998881 @default.
• W3138550658 cites W2101398993 @default.
• W3138550658 cites W2122613011 @default.
• W3138550658 cites W2135646847 @default.
• W3138550658 cites W2164059021 @default.
• W3138550658 cites W2164186760 @default.
• W3138550658 cites W2168397789 @default.
• W3138550658 cites W2302003756 @default.
• W3138550658 cites W2405265234 @default.
• W3138550658 cites W2463800533 @default.
• W3138550658 cites W2534656414 @default.
• W3138550658 cites W2574422337 @default.
• W3138550658 cites W2744761757 @default.
• W3138550658 cites W2765919958 @default.
• W3138550658 cites W2766069545 @default.
• W3138550658 cites W2768721825 @default.
• W3138550658 cites W2777880900 @default.
• W3138550658 cites W2787333362 @default.
• W3138550658 cites W2884048133 @default.
• W3138550658 cites W2911810518 @default.
• W3138550658 cites W2943554529 @default.
• W3138550658 cites W2947519079 @default.
• W3138550658 cites W2948185025 @default.
• W3138550658 cites W2955437069 @default.
• W3138550658 cites W3009963727 @default.
• W3138550658 cites W3086659214 @default.
• W3138550658 cites W3162993738 @default.
• W3138550658 cites W4297833310 @default.
• W3138550658 doi "https://doi.org/10.2196/16846" @default.
• W3138550658 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8408756" @default.
• W3138550658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34402798" @default.
• W3138550658 hasPublicationYear "2021" @default.
• W3138550658 type Work @default.
• W3138550658 sameAs 3138550658 @default.
• W3138550658 citedByCount "2" @default.
• W3138550658 countsByYear W31385506582022 @default.
• W3138550658 countsByYear W31385506582023 @default.
• W3138550658 crossrefType "journal-article" @default.
• W3138550658 hasAuthorship W3138550658A5001488716 @default.
• W3138550658 hasAuthorship W3138550658A5007761449 @default.
• W3138550658 hasAuthorship W3138550658A5015888087 @default.
• W3138550658 hasAuthorship W3138550658A5021781781 @default.
• W3138550658 hasAuthorship W3138550658A5043285442 @default.
• W3138550658 hasAuthorship W3138550658A5046465972 @default.
• W3138550658 hasAuthorship W3138550658A5062037948 @default.
• W3138550658 hasAuthorship W3138550658A5069669005 @default.
• W3138550658 hasAuthorship W3138550658A5072331751 @default.
• W3138550658 hasAuthorship W3138550658A5087877314 @default.
• W3138550658 hasAuthorship W3138550658A5090126800 @default.
• W3138550658 hasBestOaLocation W31385506581 @default.
• W3138550658 hasConcept C121608353 @default.
• W3138550658 hasConcept C126322002 @default.
• W3138550658 hasConcept C1862650 @default.
• W3138550658 hasConcept C188816634 @default.
• W3138550658 hasConcept C201903717 @default.
• W3138550658 hasConcept C2776214593 @default.
• W3138550658 hasConcept C526805850 @default.
• W3138550658 hasConcept C551997983 @default.
• W3138550658 hasConcept C71924100 @default.
• W3138550658 hasConcept C72563966 @default.
• W3138550658 hasConcept C74909509 @default.
• W3138550658 hasConceptScore W3138550658C121608353 @default.
• W3138550658 hasConceptScore W3138550658C126322002 @default.
• W3138550658 hasConceptScore W3138550658C1862650 @default.
• W3138550658 hasConceptScore W3138550658C188816634 @default.
• W3138550658 hasConceptScore W3138550658C201903717 @default.
• W3138550658 hasConceptScore W3138550658C2776214593 @default.
• W3138550658 hasConceptScore W3138550658C526805850 @default.
• W3138550658 hasConceptScore W3138550658C551997983 @default.
• W3138550658 hasConceptScore W3138550658C71924100 @default.
• W3138550658 hasConceptScore W3138550658C72563966 @default.
• W3138550658 hasConceptScore W3138550658C74909509 @default.
• W3138550658 hasIssue "8" @default.
• W3138550658 hasLocation W31385506581 @default.
• W3138550658 hasLocation W31385506582 @default.
• W3138550658 hasLocation W31385506583 @default.
• W3138550658 hasLocation W31385506584 @default.

• next