Matches in SemOpenAlex for { <https://semopenalex.org/work/W3138596015> ?p ?o ?g. }
- W3138596015 endingPage "2518" @default.
- W3138596015 startingPage "2491" @default.
- W3138596015 abstract "Stressful experiences evoke, among others, a rapid increase in brain (nor)epinephrine (NE) levels and a slower increase in glucocorticoid hormones (GCs) in the brain. Microglia are key regulators of neuronal function and contain receptors for NE and GCs. These brain cells may therefore potentially be involved in modulating stress effects on neuronal function and learning and memory. In this review, we discuss that stress induces (1) an increase in microglial numbers as well as (2) a shift toward a pro-inflammatory profile. These microglia have (3) impaired crosstalk with neurons and (4) disrupted glutamate signaling. Moreover, microglial immune responses after stress (5) alter the kynurenine pathway through metabolites that impair glutamatergic transmission. All these effects could be involved in the impairments in memory and in synaptic plasticity caused by (prolonged) stress, implicating microglia as a potential novel target in stress-related memory impairments." @default.
- W3138596015 created "2021-03-29" @default.
- W3138596015 creator A5000501122 @default.
- W3138596015 creator A5027637641 @default.
- W3138596015 creator A5029380319 @default.
- W3138596015 creator A5045828654 @default.
- W3138596015 creator A5057086204 @default.
- W3138596015 creator A5061052429 @default.
- W3138596015 creator A5068216423 @default.
- W3138596015 creator A5068657840 @default.
- W3138596015 creator A5086284254 @default.
- W3138596015 date "2021-05-04" @default.
- W3138596015 modified "2023-10-16" @default.
- W3138596015 title "An emerging role for microglia in stress‐effects on memory" @default.
- W3138596015 cites W1258429216 @default.
- W3138596015 cites W1440335865 @default.
- W3138596015 cites W1500090786 @default.
- W3138596015 cites W1518574168 @default.
- W3138596015 cites W1522823711 @default.
- W3138596015 cites W1548862642 @default.
- W3138596015 cites W1590854724 @default.
- W3138596015 cites W1620047260 @default.
- W3138596015 cites W1667616536 @default.
- W3138596015 cites W1906422585 @default.
- W3138596015 cites W1924003686 @default.
- W3138596015 cites W1963683520 @default.
- W3138596015 cites W1964189385 @default.
- W3138596015 cites W1965604886 @default.
- W3138596015 cites W1965666333 @default.
- W3138596015 cites W1966217317 @default.
- W3138596015 cites W1966391749 @default.
- W3138596015 cites W1969609722 @default.
- W3138596015 cites W1972165407 @default.
- W3138596015 cites W1972764647 @default.
- W3138596015 cites W1973922157 @default.
- W3138596015 cites W1975738393 @default.
- W3138596015 cites W1979987497 @default.
- W3138596015 cites W1980789245 @default.
- W3138596015 cites W1982316939 @default.
- W3138596015 cites W1982864908 @default.
- W3138596015 cites W1985001669 @default.
- W3138596015 cites W1988059569 @default.
- W3138596015 cites W1990121190 @default.
- W3138596015 cites W1990201789 @default.
- W3138596015 cites W1991805788 @default.
- W3138596015 cites W1992859583 @default.
- W3138596015 cites W1993095204 @default.
- W3138596015 cites W1993894887 @default.
- W3138596015 cites W1993976394 @default.
- W3138596015 cites W1994201230 @default.
- W3138596015 cites W1994707167 @default.
- W3138596015 cites W1996059296 @default.
- W3138596015 cites W1996642120 @default.
- W3138596015 cites W1999061159 @default.
- W3138596015 cites W1999069947 @default.
- W3138596015 cites W2003106844 @default.
- W3138596015 cites W2003185538 @default.
- W3138596015 cites W2004316996 @default.
- W3138596015 cites W2006227636 @default.
- W3138596015 cites W2007287932 @default.
- W3138596015 cites W2008810019 @default.
- W3138596015 cites W2012865678 @default.
- W3138596015 cites W2012901722 @default.
- W3138596015 cites W2013773774 @default.
- W3138596015 cites W2013906894 @default.
- W3138596015 cites W2014566626 @default.
- W3138596015 cites W2014619876 @default.
- W3138596015 cites W2015987039 @default.
- W3138596015 cites W2016674664 @default.
- W3138596015 cites W2019089897 @default.
- W3138596015 cites W2019848530 @default.
- W3138596015 cites W2021812498 @default.
- W3138596015 cites W2022794439 @default.
- W3138596015 cites W2023257087 @default.
- W3138596015 cites W2024469079 @default.
- W3138596015 cites W2025837300 @default.
- W3138596015 cites W2025921501 @default.
- W3138596015 cites W2027021810 @default.
- W3138596015 cites W2030325164 @default.
- W3138596015 cites W2030752045 @default.
- W3138596015 cites W2030976437 @default.
- W3138596015 cites W2032594882 @default.
- W3138596015 cites W2032679733 @default.
- W3138596015 cites W2033206554 @default.
- W3138596015 cites W2033617297 @default.
- W3138596015 cites W2033966441 @default.
- W3138596015 cites W2034005804 @default.
- W3138596015 cites W2035557202 @default.
- W3138596015 cites W2035598192 @default.
- W3138596015 cites W2035717344 @default.
- W3138596015 cites W2039717023 @default.
- W3138596015 cites W2041796079 @default.
- W3138596015 cites W2041964216 @default.
- W3138596015 cites W2042197302 @default.
- W3138596015 cites W2043708478 @default.
- W3138596015 cites W2044219916 @default.
- W3138596015 cites W2044404835 @default.
- W3138596015 cites W2044730840 @default.