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- W3138695362 abstract "It has been well recognized that prolactin (PRL), a pleiotropic hormone, has many functions in the brain, such as maternal behavior, neurogenesis, and neuronal plasticity, among others. Recently, it has been reported to have a significant role in neuroprotection against excitotoxicity. Glutamate excitotoxicity is a common alteration in many neurological and neurodegenerative diseases, leading to neuronal death. In this sense, several efforts have been made to decrease the progression of these pathologies. Despite various reports of PRL's neuroprotective effect against excitotoxicity, the signaling pathways that underlie this mechanism remain unclear. This review aims to describe the most recent and relevant studies on the molecular signaling pathways, particularly, PI3K/AKT, NF-κB, and JAK2/STAT5, which are currently under investigation and might be implicated in the molecular mechanisms that explain the PRL effects against excitotoxicity and neuroprotection. Remarkable neuroprotective effects of PRL might be useful in the treatment of some neurological diseases." @default.
- W3138695362 created "2021-03-29" @default.
- W3138695362 creator A5007554854 @default.
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- W3138695362 creator A5059340110 @default.
- W3138695362 creator A5081758006 @default.
- W3138695362 creator A5085305314 @default.
- W3138695362 date "2021-04-01" @default.
- W3138695362 modified "2023-09-30" @default.
- W3138695362 title "Decoding signaling pathways involved in prolactin-induced neuroprotection: A review" @default.
- W3138695362 cites W1526979969 @default.
- W3138695362 cites W1562512611 @default.
- W3138695362 cites W1564414040 @default.
- W3138695362 cites W1567544633 @default.
- W3138695362 cites W1661647511 @default.
- W3138695362 cites W1913599140 @default.
- W3138695362 cites W1919151020 @default.
- W3138695362 cites W1963092557 @default.
- W3138695362 cites W1964154428 @default.
- W3138695362 cites W1966798058 @default.
- W3138695362 cites W1967871299 @default.
- W3138695362 cites W1968030872 @default.
- W3138695362 cites W1968228842 @default.
- W3138695362 cites W1972019387 @default.
- W3138695362 cites W1975613290 @default.
- W3138695362 cites W1976278130 @default.
- W3138695362 cites W1976897228 @default.
- W3138695362 cites W1977107368 @default.
- W3138695362 cites W1979300653 @default.
- W3138695362 cites W1979487882 @default.
- W3138695362 cites W1979676825 @default.
- W3138695362 cites W1981216611 @default.
- W3138695362 cites W1982199848 @default.
- W3138695362 cites W1984234585 @default.
- W3138695362 cites W1990341525 @default.
- W3138695362 cites W1991226104 @default.
- W3138695362 cites W1991804504 @default.
- W3138695362 cites W1992925059 @default.
- W3138695362 cites W1994392135 @default.
- W3138695362 cites W1995024997 @default.
- W3138695362 cites W1996305746 @default.
- W3138695362 cites W1996568613 @default.
- W3138695362 cites W1996833241 @default.
- W3138695362 cites W1998319637 @default.
- W3138695362 cites W1998369738 @default.
- W3138695362 cites W1999935838 @default.
- W3138695362 cites W2004569578 @default.
- W3138695362 cites W2005614483 @default.
- W3138695362 cites W2006594678 @default.
- W3138695362 cites W2010025861 @default.
- W3138695362 cites W2014016269 @default.
- W3138695362 cites W2014291090 @default.
- W3138695362 cites W2015253610 @default.
- W3138695362 cites W2016852812 @default.
- W3138695362 cites W2020875833 @default.
- W3138695362 cites W2028841311 @default.
- W3138695362 cites W2030601224 @default.
- W3138695362 cites W2031796931 @default.
- W3138695362 cites W2033427219 @default.
- W3138695362 cites W2034389396 @default.
- W3138695362 cites W2034408892 @default.
- W3138695362 cites W2036403602 @default.
- W3138695362 cites W2038546814 @default.
- W3138695362 cites W2039743252 @default.
- W3138695362 cites W2040175075 @default.
- W3138695362 cites W2040992601 @default.
- W3138695362 cites W2041693192 @default.
- W3138695362 cites W2041969644 @default.
- W3138695362 cites W2042261461 @default.
- W3138695362 cites W2042624243 @default.
- W3138695362 cites W2048121649 @default.
- W3138695362 cites W2050479720 @default.
- W3138695362 cites W2053336673 @default.
- W3138695362 cites W2053457624 @default.
- W3138695362 cites W2055352148 @default.
- W3138695362 cites W2058936669 @default.
- W3138695362 cites W2059754026 @default.
- W3138695362 cites W2059787141 @default.
- W3138695362 cites W2059810727 @default.
- W3138695362 cites W2062386682 @default.
- W3138695362 cites W2064253775 @default.
- W3138695362 cites W2067690802 @default.
- W3138695362 cites W2067786920 @default.
- W3138695362 cites W2072735944 @default.
- W3138695362 cites W2073570284 @default.
- W3138695362 cites W2074584933 @default.
- W3138695362 cites W2074600101 @default.
- W3138695362 cites W2076573882 @default.
- W3138695362 cites W2076582794 @default.
- W3138695362 cites W2077462719 @default.
- W3138695362 cites W2077737919 @default.
- W3138695362 cites W2077911533 @default.
- W3138695362 cites W2078689306 @default.
- W3138695362 cites W2082133398 @default.
- W3138695362 cites W2083004303 @default.
- W3138695362 cites W2083896329 @default.
- W3138695362 cites W2087436174 @default.