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- W3138704433 endingPage "2076" @default.
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- W3138704433 abstract "Chronic diarrhea is a frequent presenting symptom, both in primary care medicine and in specialized gastroenterology units. It is estimated that more than 5% of the global population suffers from chronic diarrhea. and that about 40% of these subjects are older than 60 years. The clinician is frequently faced with the need to decide which is the best therapeutic approach for these patients. While the origin of chronic diarrhea is diverse, impairment of intestinal barrier function, dysbiosis. and mucosal micro-inflammation are being increasingly recognized as underlying phenomena characterizing a variety of chronic diarrheal diseases. In addition to current pharmacological therapies, there is growing interest in alternative products such as mucoprotectants, which form a mucoadhesive film over the epithelium to reduce and protect against the development of altered intestinal permeability, dysbiosis, and mucosal micro-inflammation. This manuscript focuses on chronic diarrhea in adults, and we will review recent evidence on the ability of these natural compounds to improve symptoms associated with chronic diarrhea and to exert protective effects for the intestinal barrier." @default.
- W3138704433 created "2021-03-29" @default.
- W3138704433 creator A5021051450 @default.
- W3138704433 creator A5039835312 @default.
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- W3138704433 creator A5072464359 @default.
- W3138704433 creator A5082794035 @default.
- W3138704433 date "2021-03-18" @default.
- W3138704433 modified "2023-10-07" @default.
- W3138704433 title "The Role of Purported Mucoprotectants in Dealing with Irritable Bowel Syndrome, Functional Diarrhea, and Other Chronic Diarrheal Disorders in Adults" @default.
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