FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3138768105> ?p ?o ?g. }

• W3138768105 endingPage "141" @default.
• W3138768105 startingPage "136" @default.
• W3138768105 abstract "Purpose Chronic Obstructive Pulmonary Disease (COPD) includes chronic bronchitis, small airways disease, and emphysema. Diagnosis of COPD requires spirometric evidence and may be normal even when small airways disease or emphysema is present. Emphysema increases the risk of exacerbations, and is associated with all-cause mortality and increased risk of lung cancer. We evaluated the prevalence of emphysema in participants with and without a prior history of COPD. Methods We reviewed a prospective cohort of 52,726 subjects who underwent baseline low dose CT screening for lung cancer from 2003 to 2016 in the International Early Lung Cancer Action Program. Results Of 52,726 participants, 23.8%(12,542) had CT evidence of emphysema. Of these 12,542 participants with emphysema, 76.5%(9595/12,542) had no prior COPD diagnosis even though 23.6% (2258/9595) had moderate or severe emphysema. Among 12,542 participants, significant predictors of no prior COPD diagnosis were: male (OR = 1.47, p < 0.0001), younger age (ORage10 = 0.72, p < 0.0001), lower pack-years of smoking (OR10pack-years = 0.90, p < 0.0001), completed college or higher (OR = 1.54, p < 0.0001), no family history of lung cancer (OR = 1.12, p = 0.04), no self-reported cardiac disease (OR = 0.76, p = 0.0003) or hypertension (OR = 0.74, p < 0.0001). The severity of emphysema was significantly lower among the 9595 participants with no prior COPD diagnosis, the OR for moderate emphysema was ORmoderate = 0.58(p = 0.0007) and for severe emphysema, it was ORsevere = 0.23(p < 0.0001). Conclusion Emphysema was identified in 23.8% participants undergoing LDCT and was unsuspected in 76.5%. LDCT provides an opportunity to identify emphysema, and recommend smoking cessation." @default.
• W3138768105 created "2021-03-29" @default.
• W3138768105 creator A5000408050 @default.
• W3138768105 creator A5002521084 @default.
• W3138768105 creator A5003735134 @default.
• W3138768105 creator A5004022151 @default.
• W3138768105 creator A5004441735 @default.
• W3138768105 creator A5004703744 @default.
• W3138768105 creator A5005025577 @default.
• W3138768105 creator A5006808503 @default.
• W3138768105 creator A5008199215 @default.
• W3138768105 creator A5008790983 @default.
• W3138768105 creator A5008905381 @default.
• W3138768105 creator A5010228005 @default.
• W3138768105 creator A5010543969 @default.
• W3138768105 creator A5012346270 @default.
• W3138768105 creator A5012613605 @default.
• W3138768105 creator A5012652944 @default.
• W3138768105 creator A5013077987 @default.
• W3138768105 creator A5013353953 @default.
• W3138768105 creator A5013708390 @default.
• W3138768105 creator A5016450087 @default.
• W3138768105 creator A5018350798 @default.
• W3138768105 creator A5020036191 @default.
• W3138768105 creator A5022322707 @default.
• W3138768105 creator A5024371092 @default.
• W3138768105 creator A5024492580 @default.
• W3138768105 creator A5027129016 @default.
• W3138768105 creator A5027825151 @default.
• W3138768105 creator A5028558780 @default.
• W3138768105 creator A5028598551 @default.
• W3138768105 creator A5028621630 @default.
• W3138768105 creator A5029016096 @default.
• W3138768105 creator A5029140865 @default.
• W3138768105 creator A5029509991 @default.
• W3138768105 creator A5031177493 @default.
• W3138768105 creator A5031329201 @default.
• W3138768105 creator A5031810462 @default.
• W3138768105 creator A5033556510 @default.
• W3138768105 creator A5034339560 @default.
• W3138768105 creator A5035601705 @default.
• W3138768105 creator A5036008725 @default.
• W3138768105 creator A5036354511 @default.
• W3138768105 creator A5036677159 @default.
• W3138768105 creator A5036803147 @default.
• W3138768105 creator A5037977755 @default.
• W3138768105 creator A5039247253 @default.
• W3138768105 creator A5042356921 @default.
• W3138768105 creator A5042860682 @default.
• W3138768105 creator A5044166963 @default.
• W3138768105 creator A5044440988 @default.
• W3138768105 creator A5046049042 @default.
• W3138768105 creator A5046176020 @default.
• W3138768105 creator A5048405646 @default.
• W3138768105 creator A5048675911 @default.
• W3138768105 creator A5049501437 @default.
• W3138768105 creator A5049504077 @default.
• W3138768105 creator A5050848972 @default.
• W3138768105 creator A5051170847 @default.
• W3138768105 creator A5051485828 @default.
• W3138768105 creator A5051929518 @default.
• W3138768105 creator A5052242334 @default.
• W3138768105 creator A5052259952 @default.
• W3138768105 creator A5053754026 @default.
• W3138768105 creator A5053860857 @default.
• W3138768105 creator A5053870754 @default.
• W3138768105 creator A5056589044 @default.
• W3138768105 creator A5057815702 @default.
• W3138768105 creator A5058951588 @default.
• W3138768105 creator A5060347349 @default.
• W3138768105 creator A5060527966 @default.
• W3138768105 creator A5060971465 @default.
• W3138768105 creator A5062884143 @default.
• W3138768105 creator A5064830355 @default.
• W3138768105 creator A5065697136 @default.
• W3138768105 creator A5066271889 @default.
• W3138768105 creator A5067122524 @default.
• W3138768105 creator A5067226533 @default.
• W3138768105 creator A5069377759 @default.
• W3138768105 creator A5072299555 @default.
• W3138768105 creator A5073628580 @default.
• W3138768105 creator A5075801763 @default.
• W3138768105 creator A5076123638 @default.
• W3138768105 creator A5076124945 @default.
• W3138768105 creator A5077514596 @default.
• W3138768105 creator A5078731924 @default.
• W3138768105 creator A5081817797 @default.
• W3138768105 creator A5084396616 @default.
• W3138768105 creator A5084881778 @default.
• W3138768105 creator A5086030062 @default.
• W3138768105 creator A5086615372 @default.
• W3138768105 creator A5089619585 @default.
• W3138768105 creator A5090533351 @default.
• W3138768105 creator A5090913228 @default.
• W3138768105 creator A5090923831 @default.
• W3138768105 creator A5091299701 @default.
• W3138768105 creator A5086283511 @default.
• W3138768105 date "2021-10-01" @default.

• next