FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3138806723> ?p ?o ?g. }

• W3138806723 endingPage "1702" @default.
• W3138806723 startingPage "1694" @default.
• W3138806723 abstract "Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. Environmental agents and occupational exposures may confer susceptibility to EGPA, but data are scarce. This study was undertaken to investigate the association between occupational exposures (e.g., silica, farming, asbestos, and organic solvents) and other environmental agents (e.g., smoking) and the risk of EGPA. Methods Patients with newly diagnosed EGPA (n = 111) and general population controls (n = 333) who were matched for age, sex, and geographic area of origin were recruited at a national referral center for EGPA. Exposures were assessed using a dedicated questionnaire administered by a specialist in occupational medicine, under blinded conditions. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated. Results Exposures to silica (OR 2.79 [95% CI 1.55–5.01], P = 0.001), organic solvents (OR 3.19 [95% CI 1.91–5.34], P < 0.001), and farming (OR 2.71 [95% CI 1.71–4.29], P < 0.001) were associated with an increased risk of EGPA. Co-exposure to silica and farming yielded an OR of 9.12 (95% CI 3.06–27.19, P < 0.001), suggesting a multiplicative effect between these 2 exposures. Smoking (current and former smokers combined) was significantly less frequent among patients with EGPA compared to controls (OR 0.49 [95% CI 0.29–0.70], P < 0.001). The pack-year index was also lower among patients with EGPA (OR 0.96 [95% CI 0.94–0.98], P < 0.001). The association of silica and farming was primarily aligned with ANCA-positive EGPA, while the association of smoking status and organic solvents was primarily aligned with ANCA-negative EGPA. Conclusion The environment can influence susceptibility to EGPA. Exposure to silica, farming, or organic solvents is associated with an increased risk of EGPA, while smoking is associated with a lower risk. These exposures seem to have distinct effects on different EGPA subsets." @default.
• W3138806723 created "2021-03-29" @default.
• W3138806723 creator A5003332194 @default.
• W3138806723 creator A5003385085 @default.
• W3138806723 creator A5008670556 @default.
• W3138806723 creator A5010290381 @default.
• W3138806723 creator A5022201034 @default.
• W3138806723 creator A5022516530 @default.
• W3138806723 creator A5038818711 @default.
• W3138806723 creator A5046019803 @default.
• W3138806723 creator A5046270552 @default.
• W3138806723 creator A5051735479 @default.
• W3138806723 creator A5066642738 @default.
• W3138806723 creator A5075548051 @default.
• W3138806723 creator A5078500405 @default.
• W3138806723 creator A5088474964 @default.
• W3138806723 date "2021-08-09" @default.
• W3138806723 modified "2023-10-02" @default.
• W3138806723 title "Occupational Exposures and Smoking in Eosinophilic Granulomatosis With Polyangiitis: A Case–Control Study" @default.
• W3138806723 cites W1969985614 @default.
• W3138806723 cites W1977103095 @default.
• W3138806723 cites W1988239900 @default.
• W3138806723 cites W1988433993 @default.
• W3138806723 cites W2003028807 @default.
• W3138806723 cites W2019872216 @default.
• W3138806723 cites W2020736942 @default.
• W3138806723 cites W2023946108 @default.
• W3138806723 cites W2031517139 @default.
• W3138806723 cites W2040613743 @default.
• W3138806723 cites W2053251763 @default.
• W3138806723 cites W2053826747 @default.
• W3138806723 cites W2057527493 @default.
• W3138806723 cites W2069558724 @default.
• W3138806723 cites W2070747011 @default.
• W3138806723 cites W2072085701 @default.
• W3138806723 cites W2072998173 @default.
• W3138806723 cites W2098827841 @default.
• W3138806723 cites W2104315067 @default.
• W3138806723 cites W2110321673 @default.
• W3138806723 cites W2115335990 @default.
• W3138806723 cites W2120427700 @default.
• W3138806723 cites W2122790621 @default.
• W3138806723 cites W2123714651 @default.
• W3138806723 cites W2128543516 @default.
• W3138806723 cites W2133097065 @default.
• W3138806723 cites W2142122741 @default.
• W3138806723 cites W2143738433 @default.
• W3138806723 cites W2150006445 @default.
• W3138806723 cites W2150198580 @default.
• W3138806723 cites W2150534327 @default.
• W3138806723 cites W2163012166 @default.
• W3138806723 cites W2778630295 @default.
• W3138806723 cites W2953687483 @default.
• W3138806723 cites W2957204701 @default.
• W3138806723 cites W2958012222 @default.
• W3138806723 cites W3015505099 @default.
• W3138806723 cites W3021513201 @default.
• W3138806723 cites W3087336541 @default.
• W3138806723 doi "https://doi.org/10.1002/art.41722" @default.
• W3138806723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33750006" @default.
• W3138806723 hasPublicationYear "2021" @default.
• W3138806723 type Work @default.
• W3138806723 sameAs 3138806723 @default.
• W3138806723 citedByCount "10" @default.
• W3138806723 countsByYear W31388067232022 @default.
• W3138806723 countsByYear W31388067232023 @default.
• W3138806723 crossrefType "journal-article" @default.
• W3138806723 hasAuthorship W3138806723A5003332194 @default.
• W3138806723 hasAuthorship W3138806723A5003385085 @default.
• W3138806723 hasAuthorship W3138806723A5008670556 @default.
• W3138806723 hasAuthorship W3138806723A5010290381 @default.
• W3138806723 hasAuthorship W3138806723A5022201034 @default.
• W3138806723 hasAuthorship W3138806723A5022516530 @default.
• W3138806723 hasAuthorship W3138806723A5038818711 @default.
• W3138806723 hasAuthorship W3138806723A5046019803 @default.
• W3138806723 hasAuthorship W3138806723A5046270552 @default.
• W3138806723 hasAuthorship W3138806723A5051735479 @default.
• W3138806723 hasAuthorship W3138806723A5066642738 @default.
• W3138806723 hasAuthorship W3138806723A5075548051 @default.
• W3138806723 hasAuthorship W3138806723A5078500405 @default.
• W3138806723 hasAuthorship W3138806723A5088474964 @default.
• W3138806723 hasConcept C126322002 @default.
• W3138806723 hasConcept C142724271 @default.
• W3138806723 hasConcept C156957248 @default.
• W3138806723 hasConcept C191897082 @default.
• W3138806723 hasConcept C192562407 @default.
• W3138806723 hasConcept C2776015282 @default.
• W3138806723 hasConcept C2779134260 @default.
• W3138806723 hasConcept C2779758542 @default.
• W3138806723 hasConcept C2781229154 @default.
• W3138806723 hasConcept C2908647359 @default.
• W3138806723 hasConcept C44249647 @default.
• W3138806723 hasConcept C510490043 @default.
• W3138806723 hasConcept C71924100 @default.
• W3138806723 hasConcept C99454951 @default.
• W3138806723 hasConceptScore W3138806723C126322002 @default.
• W3138806723 hasConceptScore W3138806723C142724271 @default.
• W3138806723 hasConceptScore W3138806723C156957248 @default.

• next