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• W3138822371 endingPage "861" @default.
• W3138822371 startingPage "861" @default.
• W3138822371 abstract "Chelonid alphaherpesviruses 5 and 6 (ChHV5 and ChHV6) are viruses that affect wild sea turtle populations. ChHV5 is associated with the neoplastic disease fibropapillomatosis (FP), which affects green turtles (Chelonia mydas) in panzootic proportions. ChHV6 infection is associated with lung-eye-trachea disease (LETD), which has only been observed in maricultured sea turtles, although antibodies to ChHV6 have been detected in free-ranging turtles. To better understand herpesvirus prevalence and host immunity in various green turtle foraging aggregations in Florida, USA, our objectives were to compare measures of innate and adaptive immune function in relation to (1) FP tumor presence and severity, and (2) ChHV5 and ChHV6 infection status. Free-ranging, juvenile green turtles (N = 45) were captured and examined for external FP tumors in Florida’s Big Bend, Indian River Lagoon, and Lake Worth Lagoon. Blood samples were collected upon capture and analyzed for ChHV5 and ChHV6 DNA, antibodies to ChHV5 and ChHV6, in vitro lymphocyte proliferation using a T-cell mitogen (concanavalin A), and natural killer cell activity. Despite an overall high FP prevalence (56%), ChHV5 DNA was only observed in one individual, whereas 20% of turtles tested positive for antibodies to ChHV5. ChHV6 DNA was not observed in any animals and only one turtle tested positive for ChHV6 antibodies. T-cell proliferation was not significantly related to FP presence, tumor burden, or ChHV5 seroprevalence; however, lymphocyte proliferation in response to concanavalin A was decreased in turtles with severe FP (N = 3). Lastly, green turtles with FP (N = 9) had significantly lower natural killer cell activity compared to FP-free turtles (N = 5). These results increase our understanding of immune system effects related to FP and provide evidence that immunosuppression occurs after the onset of FP disease." @default.
• W3138822371 created "2021-03-29" @default.
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• W3138822371 date "2021-03-18" @default.
• W3138822371 modified "2023-10-01" @default.
• W3138822371 title "Insights on Immune Function in Free-Ranging Green Sea Turtles (Chelonia mydas) with and without Fibropapillomatosis" @default.
• W3138822371 cites W1175046692 @default.
• W3138822371 cites W1598843567 @default.
• W3138822371 cites W1771695205 @default.
• W3138822371 cites W1826061353 @default.
• W3138822371 cites W1928377279 @default.
• W3138822371 cites W1964024000 @default.
• W3138822371 cites W1965551798 @default.
• W3138822371 cites W1965906165 @default.
• W3138822371 cites W1966478716 @default.
• W3138822371 cites W1967023861 @default.
• W3138822371 cites W1970753581 @default.
• W3138822371 cites W1978339440 @default.
• W3138822371 cites W1980054079 @default.
• W3138822371 cites W1983254416 @default.
• W3138822371 cites W1987504134 @default.
• W3138822371 cites W1992903931 @default.
• W3138822371 cites W1997334693 @default.
• W3138822371 cites W2006480821 @default.
• W3138822371 cites W2007739865 @default.
• W3138822371 cites W2009745195 @default.
• W3138822371 cites W2013262550 @default.
• W3138822371 cites W2016194279 @default.
• W3138822371 cites W2040822379 @default.
• W3138822371 cites W2044896895 @default.
• W3138822371 cites W2047381873 @default.
• W3138822371 cites W2047870349 @default.
• W3138822371 cites W2051433836 @default.
• W3138822371 cites W2051564410 @default.
• W3138822371 cites W2055043387 @default.
• W3138822371 cites W2060210670 @default.
• W3138822371 cites W2068629159 @default.
• W3138822371 cites W2068815253 @default.
• W3138822371 cites W2070867814 @default.
• W3138822371 cites W2082615392 @default.
• W3138822371 cites W2105569745 @default.
• W3138822371 cites W2109113178 @default.
• W3138822371 cites W2122143739 @default.
• W3138822371 cites W2126655521 @default.
• W3138822371 cites W2132443915 @default.
• W3138822371 cites W2133794718 @default.
• W3138822371 cites W2135219068 @default.
• W3138822371 cites W2135656045 @default.
• W3138822371 cites W2137223485 @default.
• W3138822371 cites W2143911133 @default.
• W3138822371 cites W2144406184 @default.
• W3138822371 cites W2145428892 @default.
• W3138822371 cites W2147807123 @default.
• W3138822371 cites W2150857917 @default.
• W3138822371 cites W2157339684 @default.
• W3138822371 cites W2164777277 @default.
• W3138822371 cites W2169408953 @default.
• W3138822371 cites W2170286884 @default.
• W3138822371 cites W2177830830 @default.
• W3138822371 cites W2179292624 @default.
• W3138822371 cites W2180625034 @default.
• W3138822371 cites W2265554223 @default.
• W3138822371 cites W2284297636 @default.
• W3138822371 cites W2314564036 @default.
• W3138822371 cites W2319333364 @default.
• W3138822371 cites W2321429840 @default.
• W3138822371 cites W2340978409 @default.
• W3138822371 cites W2567002388 @default.
• W3138822371 cites W2608519403 @default.
• W3138822371 cites W2728206765 @default.
• W3138822371 cites W2748483764 @default.
• W3138822371 cites W2790312041 @default.
• W3138822371 cites W2794073792 @default.
• W3138822371 cites W2803512558 @default.
• W3138822371 cites W2806149925 @default.
• W3138822371 cites W2810812406 @default.
• W3138822371 cites W2918692941 @default.
• W3138822371 cites W2972409312 @default.
• W3138822371 cites W2991204151 @default.
• W3138822371 cites W2998315690 @default.
• W3138822371 cites W3000576176 @default.
• W3138822371 cites W3015424327 @default.
• W3138822371 cites W3017298801 @default.
• W3138822371 cites W3093613927 @default.
• W3138822371 cites W3097735335 @default.

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