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- W3138914596 abstract "The Revised Atlanta Classification (RAC) and Determinant-Based Classification (DBC) are currently two widely adopted systems for evaluating the severity of acute pancreatitis (AP). This study aimed to overcome the inaccuracies and limitations that existed in them.We retrospectively analyzed 298 patients with AP. The Two-Step approach was divided into an early organ failure (OF) assessment: (I) none, (II) transient, (III) single persistent, and (IV) multiple persistent; and a later local complications assessment: (A) none, (B) sterile, and (C) infectious. Patients with AP who died before the second step were classified into category X. The Two-Step approach was then compared to the RAC and DBC.As the patients' grades increased (I to IV), organ support treatment rates, intensive care unit lengths of stay, and mortalities increased. Invasive intervention rates displayed increasing trends with local complications aggravated (A to C). Patients in category X were older and had higher Marshall scores with the highest grades of severity.By combining the early OF grades and the late local complications, the Two-Step approach represents an accurate classification system required for stratified studies of AP, and introduces the category X as the severest forms of AP." @default.
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- W3138914596 date "2021-04-21" @default.
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- W3138914596 title "The “Two‐Step” approach for classifying the severity of acute pancreatitis: A retrospective study" @default.
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- W3138914596 doi "https://doi.org/10.1002/jhbp.943" @default.
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