Matches in SemOpenAlex for { <https://semopenalex.org/work/W3138919762> ?p ?o ?g. }
- W3138919762 endingPage "2269" @default.
- W3138919762 startingPage "2247" @default.
- W3138919762 abstract "Acute lung injury (ALI) or its aggravated stage acute respiratory distress syndrome (ARDS) may lead to a life-threatening form of respiratory failure, resulting in high mortality of up to 30-40% in most studies. Although there have been decades of research since ALI was first described in 1967, the clinical therapeutic alternatives for ALI are still in a state of limited availability. Supportive treatment and mechanical ventilation still have priority. Despite some preclinical studies demonstrating the benefit of pharmacological interventions, none of these has been proved completely effective to date. Recent advances in nanotechnology may shed new light on the pharmacotherapy of ALI. Nanomedicine possesses targeting and synergistic therapeutic capability, thus boosting pharmaceutical efficacy and mitigating the side effects. Currently, a variety of nanomedicine with diverse frameworks and functional groups have been elaborately developed, in accordance with their lung targeting ability and the pathophysiology of ALI. The in-depth review of the current literature reveals that liposomes, polymers, inorganic materials, cell membranes, platelets, and other nanomedicine approaches have conferred attractive therapeutic benefits for ALI treatment. In this review, we explore the recent progress in the study of the nanomedicine-based therapy of ALI, presenting various nanomedical approaches, drug choices, therapeutic strategies, and outcomes, thereby providing insight into the trends." @default.
- W3138919762 created "2021-03-29" @default.
- W3138919762 creator A5022162722 @default.
- W3138919762 creator A5033347927 @default.
- W3138919762 creator A5063243508 @default.
- W3138919762 creator A5073269968 @default.
- W3138919762 creator A5089270930 @default.
- W3138919762 date "2021-03-01" @default.
- W3138919762 modified "2023-10-09" @default.
- W3138919762 title "Nanomedicine-Based Therapeutics to Combat Acute Lung Injury" @default.
- W3138919762 cites W1675847437 @default.
- W3138919762 cites W1863285449 @default.
- W3138919762 cites W1865808828 @default.
- W3138919762 cites W1871753595 @default.
- W3138919762 cites W1900857190 @default.
- W3138919762 cites W1909429521 @default.
- W3138919762 cites W1969274325 @default.
- W3138919762 cites W1971662522 @default.
- W3138919762 cites W1979635268 @default.
- W3138919762 cites W1980611128 @default.
- W3138919762 cites W1980733016 @default.
- W3138919762 cites W1981903503 @default.
- W3138919762 cites W1986453396 @default.
- W3138919762 cites W1994294415 @default.
- W3138919762 cites W1994547455 @default.
- W3138919762 cites W1997255681 @default.
- W3138919762 cites W2006225923 @default.
- W3138919762 cites W2010898707 @default.
- W3138919762 cites W2019611732 @default.
- W3138919762 cites W2024530762 @default.
- W3138919762 cites W2031428283 @default.
- W3138919762 cites W2032227357 @default.
- W3138919762 cites W2032802517 @default.
- W3138919762 cites W2033842010 @default.
- W3138919762 cites W2036787123 @default.
- W3138919762 cites W2049677309 @default.
- W3138919762 cites W2050728089 @default.
- W3138919762 cites W2052045396 @default.
- W3138919762 cites W2052203880 @default.
- W3138919762 cites W2059304513 @default.
- W3138919762 cites W2067500754 @default.
- W3138919762 cites W2070003597 @default.
- W3138919762 cites W2070855360 @default.
- W3138919762 cites W2073726484 @default.
- W3138919762 cites W2077459132 @default.
- W3138919762 cites W2080750960 @default.
- W3138919762 cites W2087332992 @default.
- W3138919762 cites W2091980341 @default.
- W3138919762 cites W2094720709 @default.
- W3138919762 cites W2105232700 @default.
- W3138919762 cites W2106410542 @default.
- W3138919762 cites W2106439871 @default.
- W3138919762 cites W2112422961 @default.
- W3138919762 cites W2114494901 @default.
- W3138919762 cites W2115959782 @default.
- W3138919762 cites W2119095639 @default.
- W3138919762 cites W2130017009 @default.
- W3138919762 cites W2132040583 @default.
- W3138919762 cites W2148321601 @default.
- W3138919762 cites W2148908421 @default.
- W3138919762 cites W2149984051 @default.
- W3138919762 cites W2150691073 @default.
- W3138919762 cites W2152587789 @default.
- W3138919762 cites W2152991612 @default.
- W3138919762 cites W2154483538 @default.
- W3138919762 cites W2155062388 @default.
- W3138919762 cites W2159763561 @default.
- W3138919762 cites W2161946327 @default.
- W3138919762 cites W2166551681 @default.
- W3138919762 cites W2169351508 @default.
- W3138919762 cites W2171846126 @default.
- W3138919762 cites W2233288893 @default.
- W3138919762 cites W2291675941 @default.
- W3138919762 cites W2301467654 @default.
- W3138919762 cites W2320873518 @default.
- W3138919762 cites W2331722582 @default.
- W3138919762 cites W2336405670 @default.
- W3138919762 cites W2342300953 @default.
- W3138919762 cites W2398589532 @default.
- W3138919762 cites W2400140092 @default.
- W3138919762 cites W2413042852 @default.
- W3138919762 cites W2417428124 @default.
- W3138919762 cites W2529744408 @default.
- W3138919762 cites W2587123270 @default.
- W3138919762 cites W2610344331 @default.
- W3138919762 cites W2612098297 @default.
- W3138919762 cites W2616678861 @default.
- W3138919762 cites W2630251658 @default.
- W3138919762 cites W2646209392 @default.
- W3138919762 cites W2751683279 @default.
- W3138919762 cites W2758133446 @default.
- W3138919762 cites W2769636761 @default.
- W3138919762 cites W2778564930 @default.
- W3138919762 cites W2779573058 @default.
- W3138919762 cites W2792890218 @default.
- W3138919762 cites W2793513555 @default.
- W3138919762 cites W2793547752 @default.
- W3138919762 cites W2797140742 @default.