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- W3138978286 endingPage "484" @default.
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- W3138978286 abstract "Polymer nanoparticles (NPs) have attracted significant interest in the past years for drug delivery and triggered release. However, it remains a significant challenge to produce polymer NPs with controlled properties and tunable drug loading. Traditional nanoprecipitation often leads to low drug loading. This study reports the development of a new microfluidic nanoprecipitation approach for making polymer NPs with tunable drug loading up to 50%. The synthesized curcumin-loaded shellac NPs remain very stable for the period of our experiments (10 days) under acidic conditions (pH 4.5), but release the payload at neutral pH in a sustained manner. This work provides a new strategy for making drug-loaded polymer NPs with tunable drug loading and triggered release." @default.
- W3138978286 created "2021-03-29" @default.
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- W3138978286 date "2021-07-01" @default.
- W3138978286 modified "2023-10-15" @default.
- W3138978286 title "Microfluidic synthesis of curcumin loaded polymer nanoparticles with tunable drug loading and pH-triggered release" @default.
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- W3138978286 doi "https://doi.org/10.1016/j.jcis.2021.03.035" @default.
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