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• W3138978551 abstract "Peptides can be used as an important recourse for targeted delivery of drug, as it is highly specific and selective. In recent years different peptides are significantly used as carrier to deliver various antineoplastic agents and used as one of the most promising therapeutic ligands in nanotechnology to treat cancer. Short peptides such as di- and tri-peptides play an important role in this respect, as they are very small in structure, biocompatible, and can be modified easily. Peptides such as cyclic, α-helical, linear, and amphiphilic can self-assemble to form different nanostructures such as nanorods, nanospheres, nanotubes, and nanofibers. Preclinical and clinical studies of these self-assembled peptides containing several antineoplastic agents such as curcumin, paclitaxel, and doxorubicin have already been investigated successfully. Physiologically stable di-peptides are more advantageous over other peptides, as they are less toxic and biodegradable. In recent years peptide-drug conjugates are acting as one of the prominent drug delivery carriers in targeted delivery of anticancer drugs, as they are simple to prepare, economic, and versatile." @default.
• W3138978551 created "2021-03-29" @default.
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• W3138978551 date "2021-01-01" @default.
• W3138978551 modified "2023-10-02" @default.
• W3138978551 title "Peptide-drug conjugates in targeted drug delivery to cancer" @default.
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• W3138978551 doi "https://doi.org/10.1016/b978-0-12-821712-2.00001-3" @default.
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