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- W3139056456 endingPage "796" @default.
- W3139056456 startingPage "796" @default.
- W3139056456 abstract "Every day, new information is presented with respect to how to best combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This manuscript sheds light on such recent findings, including new co-factors (i.e., neuropilin-1) and routes (i.e., olfactory transmucosal) allowing cell entry of SARS-CoV-2 and induction of neurological symptoms, as well as the new SARS-CoV-2 variants. We highlight the SARS-CoV-2 human–animal interfaces and elaborate containment strategies using the same vaccination (i.e., nanoparticle “NP” formulations of the BNT162b2 and mRNA-1273 vaccines) for humans, minks, raccoon dogs, cats, and zoo animals. We investigate the toxicity issues of anti-CoV NPs (i.e., plasmonic NPs and quantum dots) on different levels. Namely, nano–bio interfaces (i.e., protein corona), in vitro (i.e., lung cells) and in vivo (i.e., zebrafish embryos) assessments, and impacts on humans are discussed in a narrative supported by original figures. Ultimately, we express our skeptical opinion on the comprehensive administration of such antiviral nanotheranostics, even when integrated into facemasks, because of their reported toxicities and the different NP parameters (e.g., size, shape, surface charge, and purity and chemical composition of NPs) that govern their end toxicity. We believe that more toxicity studies should be performed and be presented, clarifying the odds of the safe administration of nanotoxocological solutions and the relief of a worried public." @default.
- W3139056456 created "2021-03-29" @default.
- W3139056456 creator A5007397856 @default.
- W3139056456 creator A5052281689 @default.
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- W3139056456 creator A5069916906 @default.
- W3139056456 creator A5072146060 @default.
- W3139056456 creator A5072440615 @default.
- W3139056456 date "2021-03-19" @default.
- W3139056456 modified "2023-09-28" @default.
- W3139056456 title "COVID-19 Pandemic: What about the Safety of Anti-Coronavirus Nanoparticles?" @default.
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