Matches in SemOpenAlex for { <https://semopenalex.org/work/W3139291311> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3139291311 endingPage "1712" @default.
- W3139291311 startingPage "1700" @default.
- W3139291311 abstract "Noncompliance with assigned treatments is a common challenge in analyzing and interpreting randomized clinical trials (RCTs). One way to handle noncompliance is to estimate the complier-average causal effect (CACE), the intervention's efficacy in the subpopulation that complies with assigned treatment. In a two-step meta-analysis, one could first estimate CACE for each study, then combine them to estimate the population-averaged CACE. However, when some trials do not report noncompliance data, the two-step meta-analysis can be less efficient and potentially biased by excluding these trials. This paper proposes a flexible Bayesian hierarchical CACE framework to simultaneously account for heterogeneous and incomplete noncompliance data in a meta-analysis of RCTs. The models are motivated by and used for a meta-analysis estimating the CACE of epidural analgesia on cesarean section, in which only 10 of 27 trials reported complete noncompliance data. The new analysis includes all 27 studies and the results present new insights on the causal effect after accounting for noncompliance. Compared to the estimated risk difference of 0.8% (95% CI: -0.3%, 1.9%) given by the two-step intention-to-treat meta-analysis, the estimated CACE is 4.1% (95% CrI: -0.3%, 10.5%). We also report simulation studies to evaluate the performance of the proposed method." @default.
- W3139291311 created "2021-03-29" @default.
- W3139291311 creator A5000639751 @default.
- W3139291311 creator A5014270790 @default.
- W3139291311 creator A5028016335 @default.
- W3139291311 date "2021-04-27" @default.
- W3139291311 modified "2023-09-30" @default.
- W3139291311 title "A Bayesian Hierarchical CACE Model Accounting for Incomplete Noncompliance With Application to a Meta-analysis of Epidural Analgesia on Cesarean Section" @default.
- W3139291311 cites W186268426 @default.
- W3139291311 cites W1970966688 @default.
- W3139291311 cites W1972658461 @default.
- W3139291311 cites W1976566530 @default.
- W3139291311 cites W1977579401 @default.
- W3139291311 cites W1984753671 @default.
- W3139291311 cites W1992781455 @default.
- W3139291311 cites W2003231569 @default.
- W3139291311 cites W2009871470 @default.
- W3139291311 cites W2045657044 @default.
- W3139291311 cites W2051536578 @default.
- W3139291311 cites W2055082318 @default.
- W3139291311 cites W2057765075 @default.
- W3139291311 cites W2083875149 @default.
- W3139291311 cites W2088375819 @default.
- W3139291311 cites W2100708704 @default.
- W3139291311 cites W2117770228 @default.
- W3139291311 cites W2125796111 @default.
- W3139291311 cites W2132759441 @default.
- W3139291311 cites W2133531206 @default.
- W3139291311 cites W2144512268 @default.
- W3139291311 cites W2147527890 @default.
- W3139291311 cites W2148534890 @default.
- W3139291311 cites W2165656368 @default.
- W3139291311 cites W2172100839 @default.
- W3139291311 cites W2755833300 @default.
- W3139291311 cites W2788861300 @default.
- W3139291311 cites W2806932099 @default.
- W3139291311 cites W2913903916 @default.
- W3139291311 cites W3007691441 @default.
- W3139291311 cites W3008071303 @default.
- W3139291311 cites W3124658416 @default.
- W3139291311 cites W4239926947 @default.
- W3139291311 cites W999550118 @default.
- W3139291311 doi "https://doi.org/10.1080/01621459.2021.1900859" @default.
- W3139291311 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35261417" @default.
- W3139291311 hasPublicationYear "2021" @default.
- W3139291311 type Work @default.
- W3139291311 sameAs 3139291311 @default.
- W3139291311 citedByCount "2" @default.
- W3139291311 countsByYear W31392913112023 @default.
- W3139291311 crossrefType "journal-article" @default.
- W3139291311 hasAuthorship W3139291311A5000639751 @default.
- W3139291311 hasAuthorship W3139291311A5014270790 @default.
- W3139291311 hasAuthorship W3139291311A5028016335 @default.
- W3139291311 hasBestOaLocation W31392913112 @default.
- W3139291311 hasConcept C105795698 @default.
- W3139291311 hasConcept C107673813 @default.
- W3139291311 hasConcept C126322002 @default.
- W3139291311 hasConcept C149782125 @default.
- W3139291311 hasConcept C168563851 @default.
- W3139291311 hasConcept C2908647359 @default.
- W3139291311 hasConcept C33923547 @default.
- W3139291311 hasConcept C41008148 @default.
- W3139291311 hasConcept C71924100 @default.
- W3139291311 hasConcept C95190672 @default.
- W3139291311 hasConcept C99454951 @default.
- W3139291311 hasConceptScore W3139291311C105795698 @default.
- W3139291311 hasConceptScore W3139291311C107673813 @default.
- W3139291311 hasConceptScore W3139291311C126322002 @default.
- W3139291311 hasConceptScore W3139291311C149782125 @default.
- W3139291311 hasConceptScore W3139291311C168563851 @default.
- W3139291311 hasConceptScore W3139291311C2908647359 @default.
- W3139291311 hasConceptScore W3139291311C33923547 @default.
- W3139291311 hasConceptScore W3139291311C41008148 @default.
- W3139291311 hasConceptScore W3139291311C71924100 @default.
- W3139291311 hasConceptScore W3139291311C95190672 @default.
- W3139291311 hasConceptScore W3139291311C99454951 @default.
- W3139291311 hasIssue "536" @default.
- W3139291311 hasLocation W31392913111 @default.
- W3139291311 hasLocation W31392913112 @default.
- W3139291311 hasLocation W31392913113 @default.
- W3139291311 hasOpenAccess W3139291311 @default.
- W3139291311 hasPrimaryLocation W31392913111 @default.
- W3139291311 hasRelatedWork W2507295142 @default.
- W3139291311 hasRelatedWork W2748952813 @default.
- W3139291311 hasRelatedWork W2899084033 @default.
- W3139291311 hasRelatedWork W3090452522 @default.
- W3139291311 hasRelatedWork W3120777893 @default.
- W3139291311 hasRelatedWork W3159250744 @default.
- W3139291311 hasRelatedWork W4256514411 @default.
- W3139291311 hasRelatedWork W4292236216 @default.
- W3139291311 hasRelatedWork W2083697902 @default.
- W3139291311 hasRelatedWork W2903040050 @default.
- W3139291311 hasVolume "116" @default.
- W3139291311 isParatext "false" @default.
- W3139291311 isRetracted "false" @default.
- W3139291311 magId "3139291311" @default.
- W3139291311 workType "article" @default.