Matches in SemOpenAlex for { <https://semopenalex.org/work/W3139352023> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3139352023 abstract "Background: Thrombotic Microangiopathy (TMA) is a rare disorder affecting the coagulation system causing microangiopathic thrombus formation within various blood vessels including the cerebral arteries. It may be seen in association with thrombocytopenia, anemia, purpura and kidney failure as well as complications of various systemic viral illnesses. We sought to estimate the trends, predictors, and outcomes of CeVD in patients having ™ from a nationally representative database of the USA. Methods: In this cross-sectional study, we identified hospitalization with TM using ICD-9/10-CM from the National Inpatient Sample (NIS) for the years 2008-2017. Prevalence of CeVD was identified by validated ICD-9/10-CM codes. We utilized Cochran Armitage trend test and multivariable survey logistic regression models to analyze temporal trends, outcomes and predictors of any CeVD in TM patients. Results: Out of a total 58,850 hospitalizations among TMA patients, 4,668 (7.9%) developed CeVD. Prevalence of CeVD increased from 6.2% in 2008 to 8.2% in 2017 (pTrend<0.001). Patients who developed CeVD were older and more likely to be female. In multivariable regression analysis, increasing age (OR 1.2; 95%CI 1.1-1.2; p<0.0001); females (OR 1.3; 95%CI 1.1-1.6;p<0.0004); African American (OR 1.4; 95%CI 1.2-1.7;p<0.001) and hypertension (OR 1.3; 95%CI 1.1-1.6; p<0.0001). CeVD was also associated with higher length of stay (18 vs 12 days; p<0.001). Additionally, CeVD was associated with higher in-hospital mortality (aOR 2.1; 95%CI 1.7-2.5; p<0.001) and discharge to facility (aOR 3.0; 95%CI 2.4-3.5; p<0.001) after adjusting with confounders. Conclusion: We observed the mildly incremental prevalence of CeVD among TMA patients. We were able to identify the TMA patient population susceptible to CeVD, most commonly occurring in older, females and African Americans. CeVD was also associated with significantly poor outcomes in TM. These findings may pose similarities to other systemic viral illness-induced thrombotic microangiopathy such as COVID-19. Further studies are required to improve the outcomes of these susceptible patient populations." @default.
- W3139352023 created "2021-03-29" @default.
- W3139352023 creator A5014776795 @default.
- W3139352023 creator A5020306732 @default.
- W3139352023 creator A5023928517 @default.
- W3139352023 creator A5047838033 @default.
- W3139352023 creator A5051800231 @default.
- W3139352023 creator A5056586271 @default.
- W3139352023 creator A5061745160 @default.
- W3139352023 creator A5069914947 @default.
- W3139352023 creator A5073656927 @default.
- W3139352023 creator A5075230108 @default.
- W3139352023 creator A5085509572 @default.
- W3139352023 date "2021-03-01" @default.
- W3139352023 modified "2023-10-16" @default.
- W3139352023 title "Abstract P707: Trends, Predictors and Outcomes of Cerebrovascular Disease Amongst Patients With Thrombotic Microangiopathy" @default.
- W3139352023 doi "https://doi.org/10.1161/str.52.suppl_1.p707" @default.
- W3139352023 hasPublicationYear "2021" @default.
- W3139352023 type Work @default.
- W3139352023 sameAs 3139352023 @default.
- W3139352023 citedByCount "0" @default.
- W3139352023 crossrefType "journal-article" @default.
- W3139352023 hasAuthorship W3139352023A5014776795 @default.
- W3139352023 hasAuthorship W3139352023A5020306732 @default.
- W3139352023 hasAuthorship W3139352023A5023928517 @default.
- W3139352023 hasAuthorship W3139352023A5047838033 @default.
- W3139352023 hasAuthorship W3139352023A5051800231 @default.
- W3139352023 hasAuthorship W3139352023A5056586271 @default.
- W3139352023 hasAuthorship W3139352023A5061745160 @default.
- W3139352023 hasAuthorship W3139352023A5069914947 @default.
- W3139352023 hasAuthorship W3139352023A5073656927 @default.
- W3139352023 hasAuthorship W3139352023A5075230108 @default.
- W3139352023 hasAuthorship W3139352023A5085509572 @default.
- W3139352023 hasConcept C126322002 @default.
- W3139352023 hasConcept C127413603 @default.
- W3139352023 hasConcept C134018914 @default.
- W3139352023 hasConcept C151956035 @default.
- W3139352023 hasConcept C187212893 @default.
- W3139352023 hasConcept C2776513394 @default.
- W3139352023 hasConcept C2777878052 @default.
- W3139352023 hasConcept C2778248108 @default.
- W3139352023 hasConcept C2779134260 @default.
- W3139352023 hasConcept C2780645631 @default.
- W3139352023 hasConcept C555293320 @default.
- W3139352023 hasConcept C71924100 @default.
- W3139352023 hasConcept C78519656 @default.
- W3139352023 hasConceptScore W3139352023C126322002 @default.
- W3139352023 hasConceptScore W3139352023C127413603 @default.
- W3139352023 hasConceptScore W3139352023C134018914 @default.
- W3139352023 hasConceptScore W3139352023C151956035 @default.
- W3139352023 hasConceptScore W3139352023C187212893 @default.
- W3139352023 hasConceptScore W3139352023C2776513394 @default.
- W3139352023 hasConceptScore W3139352023C2777878052 @default.
- W3139352023 hasConceptScore W3139352023C2778248108 @default.
- W3139352023 hasConceptScore W3139352023C2779134260 @default.
- W3139352023 hasConceptScore W3139352023C2780645631 @default.
- W3139352023 hasConceptScore W3139352023C555293320 @default.
- W3139352023 hasConceptScore W3139352023C71924100 @default.
- W3139352023 hasConceptScore W3139352023C78519656 @default.
- W3139352023 hasIssue "Suppl_1" @default.
- W3139352023 hasLocation W31393520231 @default.
- W3139352023 hasOpenAccess W3139352023 @default.
- W3139352023 hasPrimaryLocation W31393520231 @default.
- W3139352023 hasRelatedWork W1980143795 @default.
- W3139352023 hasRelatedWork W1995972771 @default.
- W3139352023 hasRelatedWork W2039418650 @default.
- W3139352023 hasRelatedWork W2069439332 @default.
- W3139352023 hasRelatedWork W2315197671 @default.
- W3139352023 hasRelatedWork W2359041291 @default.
- W3139352023 hasRelatedWork W2374911868 @default.
- W3139352023 hasRelatedWork W2387692709 @default.
- W3139352023 hasRelatedWork W2396523293 @default.
- W3139352023 hasRelatedWork W3210301086 @default.
- W3139352023 hasVolume "52" @default.
- W3139352023 isParatext "false" @default.
- W3139352023 isRetracted "false" @default.
- W3139352023 magId "3139352023" @default.
- W3139352023 workType "article" @default.