FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3139529346> ?p ?o ?g. }

• W3139529346 abstract "The depth of invasion (DOI) is considered an independent risk factor for occult lymph node metastasis in oral cavity squamous cell carcinoma (OCSCC). It is used to decide whether an elective neck dissection (END) is indicated in the case of a clinically negative neck for early stage carcinoma (pT1/pT2). However, there is no consensus on the cut-off value of the DOI for performing an END. The aim of this study was to determine a cut-off value for clinical decision making on END, by assessing the association of the DOI and the risk of occult lymph node metastasis in early OCSCC.A retrospective cohort study was conducted at the Erasmus MC, University Medical Centre Rotterdam, The Netherlands. Patients surgically treated for pT1/pT2 OCSCC between 2006 and 2012 were included. For all cases, the DOI was measured according to the 8th edition of the American Joint Committee on Cancer guideline. Patient characteristics, tumor characteristics (pTN, differentiation grade, perineural invasion, and lymphovascular invasion), treatment modality (END or watchful waiting), and 5-year follow-up (local recurrence, regional recurrence, and distant metastasis) were obtained from patient files.A total of 222 patients were included, 117 pT1 and 105 pT2. Occult lymph node metastasis was found in 39 of the 166 patients who received END. Univariate logistic regression analysis showed DOI to be a significant predictor for occult lymph node metastasis (odds ratio (OR) = 1.3 per mm DOI; 95% CI: 1.1-1.5, p = 0.001). At a DOI of 4.3 mm the risk of occult lymph node metastasis was >20% (all subsites combined).The DOI is a significant predictor for occult lymph node metastasis in early stage oral carcinoma. A NPV of 81% was found at a DOI cut-off value of 4 mm. Therefore, an END should be performed if the DOI is >4 mm." @default.
• W3139529346 created "2021-03-29" @default.
• W3139529346 creator A5000718251 @default.
• W3139529346 creator A5004858830 @default.
• W3139529346 creator A5009201271 @default.
• W3139529346 creator A5017212979 @default.
• W3139529346 creator A5027959991 @default.
• W3139529346 creator A5037570366 @default.
• W3139529346 creator A5038585473 @default.
• W3139529346 creator A5046531504 @default.
• W3139529346 creator A5046644889 @default.
• W3139529346 creator A5047219764 @default.
• W3139529346 creator A5050001604 @default.
• W3139529346 creator A5054970394 @default.
• W3139529346 creator A5057318768 @default.
• W3139529346 creator A5057323668 @default.
• W3139529346 creator A5058237993 @default.
• W3139529346 creator A5063981653 @default.
• W3139529346 creator A5065479377 @default.
• W3139529346 creator A5075240152 @default.
• W3139529346 creator A5078655611 @default.
• W3139529346 creator A5084361593 @default.
• W3139529346 date "2021-03-12" @default.
• W3139529346 modified "2023-10-10" @default.
• W3139529346 title "Is the Depth of Invasion a Marker for Elective Neck Dissection in Early Oral Squamous Cell Carcinoma?" @default.
• W3139529346 cites W1757407923 @default.
• W3139529346 cites W1923197151 @default.
• W3139529346 cites W1938698939 @default.
• W3139529346 cites W1968528263 @default.
• W3139529346 cites W1973784753 @default.
• W3139529346 cites W1973821414 @default.
• W3139529346 cites W1996936425 @default.
• W3139529346 cites W1997129527 @default.
• W3139529346 cites W1998665067 @default.
• W3139529346 cites W2005145657 @default.
• W3139529346 cites W2011144254 @default.
• W3139529346 cites W2013380797 @default.
• W3139529346 cites W2026066044 @default.
• W3139529346 cites W2034350373 @default.
• W3139529346 cites W2048564480 @default.
• W3139529346 cites W2087073932 @default.
• W3139529346 cites W2090235129 @default.
• W3139529346 cites W2107960772 @default.
• W3139529346 cites W2110435930 @default.
• W3139529346 cites W2121854540 @default.
• W3139529346 cites W2146362101 @default.
• W3139529346 cites W2148818765 @default.
• W3139529346 cites W2158373399 @default.
• W3139529346 cites W2203013257 @default.
• W3139529346 cites W2283809829 @default.
• W3139529346 cites W2535284666 @default.
• W3139529346 cites W2555952585 @default.
• W3139529346 cites W2579941249 @default.
• W3139529346 cites W2590976314 @default.
• W3139529346 cites W2739836417 @default.
• W3139529346 cites W2888226586 @default.
• W3139529346 cites W2889646458 @default.
• W3139529346 cites W2896123765 @default.
• W3139529346 cites W2904916589 @default.
• W3139529346 cites W2905961850 @default.
• W3139529346 cites W2906613093 @default.
• W3139529346 cites W2908494598 @default.
• W3139529346 cites W2914031129 @default.
• W3139529346 cites W2944795545 @default.
• W3139529346 cites W3047024458 @default.
• W3139529346 cites W3081203964 @default.
• W3139529346 cites W3118091883 @default.
• W3139529346 doi "https://doi.org/10.3389/fonc.2021.628320" @default.
• W3139529346 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7996205" @default.
• W3139529346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33777774" @default.
• W3139529346 hasPublicationYear "2021" @default.
• W3139529346 type Work @default.
• W3139529346 sameAs 3139529346 @default.
• W3139529346 citedByCount "20" @default.
• W3139529346 countsByYear W31395293462021 @default.
• W3139529346 countsByYear W31395293462022 @default.
• W3139529346 countsByYear W31395293462023 @default.
• W3139529346 crossrefType "journal-article" @default.
• W3139529346 hasAuthorship W3139529346A5000718251 @default.
• W3139529346 hasAuthorship W3139529346A5004858830 @default.
• W3139529346 hasAuthorship W3139529346A5009201271 @default.
• W3139529346 hasAuthorship W3139529346A5017212979 @default.
• W3139529346 hasAuthorship W3139529346A5027959991 @default.
• W3139529346 hasAuthorship W3139529346A5037570366 @default.
• W3139529346 hasAuthorship W3139529346A5038585473 @default.
• W3139529346 hasAuthorship W3139529346A5046531504 @default.
• W3139529346 hasAuthorship W3139529346A5046644889 @default.
• W3139529346 hasAuthorship W3139529346A5047219764 @default.
• W3139529346 hasAuthorship W3139529346A5050001604 @default.
• W3139529346 hasAuthorship W3139529346A5054970394 @default.
• W3139529346 hasAuthorship W3139529346A5057318768 @default.
• W3139529346 hasAuthorship W3139529346A5057323668 @default.
• W3139529346 hasAuthorship W3139529346A5058237993 @default.
• W3139529346 hasAuthorship W3139529346A5063981653 @default.
• W3139529346 hasAuthorship W3139529346A5065479377 @default.
• W3139529346 hasAuthorship W3139529346A5075240152 @default.
• W3139529346 hasAuthorship W3139529346A5078655611 @default.
• W3139529346 hasAuthorship W3139529346A5084361593 @default.
• W3139529346 hasBestOaLocation W31395293461 @default.
• W3139529346 hasConcept C121608353 @default.

• next