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• W3139536643 abstract "Abstract Objective Data on adult lung transplantation suggest perioperative benefits of intraoperative extracorporeal membrane oxygenation (ECMO) compared to cardiopulmonary bypass (CPB). Information regarding their pediatric counterparts, however, is limited. This study compares outcomes of intraoperative ECMO versus CPB in pediatric lung transplantation. Methods We reviewed all pediatric lung transplants at our institution from 2014 to 2019 and compared those supported intraoperatively on ECMO (n = 13) versus CPB (n = 22), plus a conditional analysis excluding re‐transplantations (ECMO [n = 13] versus CPB [n = 20]). We evaluated survival, surgical times, intraoperative transfusions, postoperative support, complications, and duration of hospitalization. Results Total time on ECMO support was significantly less than that of CPB support ( P = .018). Intraoperatively, the ECMO group required fewer transfusions of fresh‐frozen plasma (8.9 [5.8‐22.3] vs 16.6 [11.4‐39.0] mL/kg, P = .049) and platelets (4.2 [0.0‐6.7] vs 8.0 [3.5‐14.0] mL/kg, P = .049). When excluding re‐transplantations, patients on ECMO required fewer packed red blood cells intraoperatively (12.6 [2.1‐30.7] vs 28.2 [14.0‐54.0] mL/kg, P = .048). There were no differences in postoperative support requirements, complications, or mortality at one, six, and twelve months. Conclusions Intraoperative ECMO support during pediatric lung transplantation appears to decrease intraoperative transfusion requirements when compared to CPB. Data from additional institutions may strengthen these observations." @default.
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• W3139536643 date "2021-03-27" @default.
• W3139536643 modified "2023-10-17" @default.
• W3139536643 title "A comparison of cardiopulmonary bypass versus extracorporeal membrane oxygenation: Does intraoperative circulatory support strategy affect outcomes in pediatric lung transplantation?" @default.
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• W3139536643 doi "https://doi.org/10.1111/ctr.14289" @default.
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