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- W3139743227 abstract "It has been found that the effects of opiates and opioid peptides on RVD are of two types. Compounds of the first type such as Etor, Eton, fentanyl and prodinc derivatives, Met-and Leu-Enk and DADL are biphasic in nature. At lower concentrations (10~(-8)-10~(-5)M) they have inhibitory effects and at higher concentrations (10~(-5)-10~(-4)M) they are excitatory. Compounds of the second type, such as Mor, benzomorphan derivatives, Cyc and SKF and the antagonist Nx have virtually no or only weakly inhibitory effects but may antagonize the inhibitory effect produced by the first group of compounds at lower concontrations. MC belongs to the second type, but it cannot antagonize the inhibitory effect of β-End. The results are discussed in terms of multiple receptors, the high and low affinity binding sites, and the interrelationship between receptors." @default.
- W3139743227 created "2021-04-13" @default.
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- W3139743227 date "1983-01-01" @default.
- W3139743227 modified "2023-09-25" @default.
- W3139743227 title "THE BIPHASIC EFFECTS OF SOME OPIATES AND OPIOID PEPTIDES ON RAT VAS DEFERENS" @default.
- W3139743227 hasPublicationYear "1983" @default.
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