Matches in SemOpenAlex for { <https://semopenalex.org/work/W3140047937> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3140047937 abstract "Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV2) depends on RNA-dependent RNA polymerase (RdRp) enzyme complex for its genomic replications and thus can be inhibited by nucleoside analogues. An example is Remdesivir, which is a non-obligate chain terminator of RdRp. Therefore, we investigate the activities of Remdesivir against COVID-19.This is a systematic-review and meta-analysis of the literature on the effectiveness of Remdesivir in the management of COVID-19 through MEDLINE (from Jan 2019 to January 2021), EMBASE (from Jan 2019 to January 2021), Publics Ovidius Naso (Ovoid), Database of Abstracts of Reviews of Effects and the Cochrane Central Register of Controlled Trials in Issue 1 of 12, January 2021. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist was applied and the questions generated in conformity with the participants, interventions, comparisons, outcomes, and study design (PICOS). Statistical analysis was performed in Stata v. 12.1 (StataCorp, Texas USA).The outcome of the reviewed relevant journals and the cross-references including clinical trials, systematic reviews and metanalysis were documented. Out of 569,000 articles, 11 roundly-suited the inclusion criteria. The comparative effects of Remdesivir on death (OR = 0.79; 95% CI = 0.57, 1.08) and recovery (OR = 2.22; p5% CI = 1.80, 2.73) were calculated.Remdesivir is useful in the treatment of COVID-19 especially the severe disease. However, it should be used with caution since all the adverse effects are not known. We recommend Remdesivir as an alternative/third-force in the treatment of severe and critical COVID-19." @default.
- W3140047937 created "2021-04-13" @default.
- W3140047937 creator A5028302885 @default.
- W3140047937 creator A5054381471 @default.
- W3140047937 creator A5066054102 @default.
- W3140047937 date "2021-05-01" @default.
- W3140047937 modified "2023-09-24" @default.
- W3140047937 title "Third force in the treatment of COVID-19: A systematic review and meta-analysis" @default.
- W3140047937 cites W2161374186 @default.
- W3140047937 cites W2756578555 @default.
- W3140047937 cites W3015490759 @default.
- W3140047937 cites W3015554176 @default.
- W3140047937 cites W3018023298 @default.
- W3140047937 cites W3019392605 @default.
- W3140047937 cites W3023213585 @default.
- W3140047937 cites W3027630905 @default.
- W3140047937 cites W3032677067 @default.
- W3140047937 cites W3046832661 @default.
- W3140047937 cites W3049524783 @default.
- W3140047937 cites W3080718665 @default.
- W3140047937 cites W3082490235 @default.
- W3140047937 cites W3093244828 @default.
- W3140047937 cites W3111076045 @default.
- W3140047937 cites W3112950444 @default.
- W3140047937 cites W3119062939 @default.
- W3140047937 cites W3033313739 @default.
- W3140047937 doi "https://doi.org/10.1016/j.amsu.2021.102218" @default.
- W3140047937 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8018907" @default.
- W3140047937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33841878" @default.
- W3140047937 hasPublicationYear "2021" @default.
- W3140047937 type Work @default.
- W3140047937 sameAs 3140047937 @default.
- W3140047937 citedByCount "2" @default.
- W3140047937 countsByYear W31400479372022 @default.
- W3140047937 countsByYear W31400479372023 @default.
- W3140047937 crossrefType "journal-article" @default.
- W3140047937 hasAuthorship W3140047937A5028302885 @default.
- W3140047937 hasAuthorship W3140047937A5054381471 @default.
- W3140047937 hasAuthorship W3140047937A5066054102 @default.
- W3140047937 hasBestOaLocation W31400479371 @default.
- W3140047937 hasConcept C118552586 @default.
- W3140047937 hasConcept C126322002 @default.
- W3140047937 hasConcept C15744967 @default.
- W3140047937 hasConcept C17744445 @default.
- W3140047937 hasConcept C177713679 @default.
- W3140047937 hasConcept C180747234 @default.
- W3140047937 hasConcept C189708586 @default.
- W3140047937 hasConcept C197934379 @default.
- W3140047937 hasConcept C199539241 @default.
- W3140047937 hasConcept C27415008 @default.
- W3140047937 hasConcept C2779134260 @default.
- W3140047937 hasConcept C2779356329 @default.
- W3140047937 hasConcept C2779473830 @default.
- W3140047937 hasConcept C3008058167 @default.
- W3140047937 hasConcept C524204448 @default.
- W3140047937 hasConcept C71924100 @default.
- W3140047937 hasConcept C95190672 @default.
- W3140047937 hasConceptScore W3140047937C118552586 @default.
- W3140047937 hasConceptScore W3140047937C126322002 @default.
- W3140047937 hasConceptScore W3140047937C15744967 @default.
- W3140047937 hasConceptScore W3140047937C17744445 @default.
- W3140047937 hasConceptScore W3140047937C177713679 @default.
- W3140047937 hasConceptScore W3140047937C180747234 @default.
- W3140047937 hasConceptScore W3140047937C189708586 @default.
- W3140047937 hasConceptScore W3140047937C197934379 @default.
- W3140047937 hasConceptScore W3140047937C199539241 @default.
- W3140047937 hasConceptScore W3140047937C27415008 @default.
- W3140047937 hasConceptScore W3140047937C2779134260 @default.
- W3140047937 hasConceptScore W3140047937C2779356329 @default.
- W3140047937 hasConceptScore W3140047937C2779473830 @default.
- W3140047937 hasConceptScore W3140047937C3008058167 @default.
- W3140047937 hasConceptScore W3140047937C524204448 @default.
- W3140047937 hasConceptScore W3140047937C71924100 @default.
- W3140047937 hasConceptScore W3140047937C95190672 @default.
- W3140047937 hasLocation W31400479371 @default.
- W3140047937 hasLocation W31400479372 @default.
- W3140047937 hasLocation W31400479373 @default.
- W3140047937 hasLocation W31400479374 @default.
- W3140047937 hasOpenAccess W3140047937 @default.
- W3140047937 hasPrimaryLocation W31400479371 @default.
- W3140047937 hasRelatedWork W2121462204 @default.
- W3140047937 hasRelatedWork W2122489679 @default.
- W3140047937 hasRelatedWork W2217615980 @default.
- W3140047937 hasRelatedWork W2888951595 @default.
- W3140047937 hasRelatedWork W2901881702 @default.
- W3140047937 hasRelatedWork W2964601175 @default.
- W3140047937 hasRelatedWork W2977892363 @default.
- W3140047937 hasRelatedWork W3092753388 @default.
- W3140047937 hasRelatedWork W4328101666 @default.
- W3140047937 hasRelatedWork W4380423232 @default.
- W3140047937 hasVolume "65" @default.
- W3140047937 isParatext "false" @default.
- W3140047937 isRetracted "false" @default.
- W3140047937 magId "3140047937" @default.
- W3140047937 workType "article" @default.