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- W3140149280 abstract "AIM: To investigate affection of the novel Ginko biloba extract GBE50 on bcl-2、bcl-xL gene expression in rabbit myocardium. METHODS: Adult male New Zealand rabbits were randomly divided into 2 groups. GBE50 group were orally administrated with 100 mg/kg GBE50 daily. Control group were only administrated vehicle 2% CMC-Na. After being raised for 4 weeks, the animals were killed and the ventricular tissue were excised. We performed reverse transcriptase polymerase (RT-PCR) to measure gene expression of bcl-2、bcl-xL. Semiquantitative analysis method based on gel electrophoresis image was adopted to compare gene expression among groups. RESULTS : The gene expression of bcl-2、bcl-xL significantly increased in GBE50 group compared with control group. CONCLUSION: The novel Ginko biloba extract GBE50 can promote expression of the antiapoptotic gene bcl-2、bcl-xL in rabbit myocardium." @default.
- W3140149280 created "2021-04-13" @default.
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- W3140149280 date "2005-01-01" @default.
- W3140149280 modified "2023-09-24" @default.
- W3140149280 title "Effect of gene expression of bcl-2 and bcl-xL in rabbit myocardium by Ginko biloba extract GBE50" @default.
- W3140149280 hasPublicationYear "2005" @default.
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