Matches in SemOpenAlex for { <https://semopenalex.org/work/W3140211486> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W3140211486 abstract "Abstract Toll/interleukin -1 receptor (TIR) domains, which have NAD + cleavage activity, are used as signaling modules in NOD-like receptors for defense responses. It has been shown that TIR domains not only form homo- or heterodimers with TIR domain-containing proteins but also interact with various proteins. A previous study showed that overexpression of Arabidopsis thaliana (Arabidopsis) AtTX14 , encoding an N-terminal TIR domain and a C-terminal domain with unknown function, resulted in dwarfism and constitutive defense signaling or autoimmunity. Transgenic Arabidopsis overexpressing AtTX14 displays enhanced defense responses and associated dwarf phenotypes at 28 °C compared with those at 22 °C, which differs from other mutant or transgenic Arabidopsis with constitutive defense responses. We found that AtTX14 is alternatively spliced to encode three different proteins, and the TIR domain itself can induce autoimmunity and elevated defense responses to the bacterial pathogen Pseudomonas syringae pv. tomato . In addition, we revealed that the transcription of AtTX14 is regulated by a positive feedback mechanism. With transient overexpression of three AtTX14 protein forms in tobacco leaves, providing a heterologous system free from the positive feedback of AtTX14 in Arabidopsis, we demonstrated that expression of a splicing variant encoding the TIR domain-only protein is sufficient to activate defense signaling. A deeper understanding of interaction networks involving AtTX14 will broaden our knowledge on how plant defense signaling is regulated in response to pathogen infection and ambient temperature changes." @default.
- W3140211486 created "2021-04-13" @default.
- W3140211486 creator A5003739313 @default.
- W3140211486 creator A5033239374 @default.
- W3140211486 creator A5077579313 @default.
- W3140211486 creator A5082809662 @default.
- W3140211486 date "2021-04-03" @default.
- W3140211486 modified "2023-09-27" @default.
- W3140211486 title "Toll/interleukin-1 Receptor Domain-Only Protein of Arabidopsis Thaliana AtTX14 2IR, Produced By Alternative Splicing, Can Induce Defense Responses" @default.
- W3140211486 doi "https://doi.org/10.21203/rs.3.rs-378145/v1" @default.
- W3140211486 hasPublicationYear "2021" @default.
- W3140211486 type Work @default.
- W3140211486 sameAs 3140211486 @default.
- W3140211486 citedByCount "0" @default.
- W3140211486 crossrefType "posted-content" @default.
- W3140211486 hasAuthorship W3140211486A5003739313 @default.
- W3140211486 hasAuthorship W3140211486A5033239374 @default.
- W3140211486 hasAuthorship W3140211486A5077579313 @default.
- W3140211486 hasAuthorship W3140211486A5082809662 @default.
- W3140211486 hasBestOaLocation W31402114861 @default.
- W3140211486 hasConcept C102230213 @default.
- W3140211486 hasConcept C104317684 @default.
- W3140211486 hasConcept C143065580 @default.
- W3140211486 hasConcept C170493617 @default.
- W3140211486 hasConcept C194583182 @default.
- W3140211486 hasConcept C2775988993 @default.
- W3140211486 hasConcept C2779491563 @default.
- W3140211486 hasConcept C2780115692 @default.
- W3140211486 hasConcept C2780381237 @default.
- W3140211486 hasConcept C53345823 @default.
- W3140211486 hasConcept C54355233 @default.
- W3140211486 hasConcept C54458228 @default.
- W3140211486 hasConcept C62478195 @default.
- W3140211486 hasConcept C67705224 @default.
- W3140211486 hasConcept C86339819 @default.
- W3140211486 hasConcept C86803240 @default.
- W3140211486 hasConcept C95444343 @default.
- W3140211486 hasConceptScore W3140211486C102230213 @default.
- W3140211486 hasConceptScore W3140211486C104317684 @default.
- W3140211486 hasConceptScore W3140211486C143065580 @default.
- W3140211486 hasConceptScore W3140211486C170493617 @default.
- W3140211486 hasConceptScore W3140211486C194583182 @default.
- W3140211486 hasConceptScore W3140211486C2775988993 @default.
- W3140211486 hasConceptScore W3140211486C2779491563 @default.
- W3140211486 hasConceptScore W3140211486C2780115692 @default.
- W3140211486 hasConceptScore W3140211486C2780381237 @default.
- W3140211486 hasConceptScore W3140211486C53345823 @default.
- W3140211486 hasConceptScore W3140211486C54355233 @default.
- W3140211486 hasConceptScore W3140211486C54458228 @default.
- W3140211486 hasConceptScore W3140211486C62478195 @default.
- W3140211486 hasConceptScore W3140211486C67705224 @default.
- W3140211486 hasConceptScore W3140211486C86339819 @default.
- W3140211486 hasConceptScore W3140211486C86803240 @default.
- W3140211486 hasConceptScore W3140211486C95444343 @default.
- W3140211486 hasLocation W31402114861 @default.
- W3140211486 hasOpenAccess W3140211486 @default.
- W3140211486 hasPrimaryLocation W31402114861 @default.
- W3140211486 hasRelatedWork W1983725845 @default.
- W3140211486 hasRelatedWork W2034981606 @default.
- W3140211486 hasRelatedWork W2037211021 @default.
- W3140211486 hasRelatedWork W2092388446 @default.
- W3140211486 hasRelatedWork W2101920100 @default.
- W3140211486 hasRelatedWork W2126039435 @default.
- W3140211486 hasRelatedWork W2138625184 @default.
- W3140211486 hasRelatedWork W2138961536 @default.
- W3140211486 hasRelatedWork W2157427822 @default.
- W3140211486 hasRelatedWork W61987662 @default.
- W3140211486 isParatext "false" @default.
- W3140211486 isRetracted "false" @default.
- W3140211486 magId "3140211486" @default.
- W3140211486 workType "article" @default.