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- W3140219954 abstract "The aryltetralin-type lignan podophyllotoxin,the main agent present in the resin extracted from the rhizomes of differentpodophyllum species,possesses important antineoplastic and antiviral properties and has been widely used in diverse cultures sinceancient times for medicinal purposes as a cathartic and antihelminthic agent.Today,podophyllotoxin serves as the starting material forthe preparation of the well-known cytostatic agents:etoposide and teniposide which are used in combination therapies with other drugsfor the treatment of a variety of malignancies.The present review focuses on the lead compound,that is,podophyllotoxin and summarizesits structural characteristics,natural sources,biological activities,novel derivatives,medicinal applications and future perspectives." @default.
- W3140219954 created "2021-04-13" @default.
- W3140219954 creator A5064734247 @default.
- W3140219954 date "2012-01-01" @default.
- W3140219954 modified "2023-10-04" @default.
- W3140219954 title "Podophyllotoxin,a medicinal agent of plant origin:past,present and future" @default.
- W3140219954 hasPublicationYear "2012" @default.
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