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- W3140355992 abstract "外国 nucleic 酸,入侵充当危险信号为的病原体的必要签名分子招待房间,被 endosomal nucleic 检测酸察觉到的像使用费的受体(TLR ) 3, 7, 8, 9,和 13。这些 TLR 演变在 endosomal 分隔空间以内认出非自我 nucleic 酸并且很快开始天生的有免疫力的回答通过类型的正式就职保证宿主保护我干扰素,煽动性的 cytokines, chemokines,和 co-stimulatory 分子和有免疫力的细胞的成熟。在这评论,我们通过 endosomal nucleic 加亮我们联系病原体的 nucleic 酸的识别和相应发信号的小径的激活的理解酸察觉到的 TLR 3 , 7 , 8 , 9 ,和 13 为病原体的庞大的差异与他们的区分上的特别强调,细胞内部的 trafficking ,解朊的劈开, autophagy ,和规章的节目。" @default.
- W3140355992 created "2021-04-13" @default.
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- W3140355992 date "2013-01-01" @default.
- W3140355992 modified "2023-09-24" @default.
- W3140355992 title "Recognition of pathogen-associated nucleic acids by endosomal nucleic acid-sensing toll-like receptors" @default.
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