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- W3140428462 abstract "Objectives: To evaluate the anti-fatigue, immune-enhancing, auxiliary lipid-lowering and auxiliary hypoglycemic effects of apple cider vinegar fortified with Cordyceps militaris polysaccharides orally administered to mice. Methods: Cordyceps militaris polysaccharides were extracted from the fruit bodies of Cordyceps militaris. Apple cider vinegar was prepared by alcoholic and subsequent acetous fermentation of apple juice and formulated into a functional beverage with the addition of the fungal polysaccharides. After adult mice were orally administered with different dosages of the apple vinegar beverage, weight-loaded forced swimming time, liver glycogen content and blood lactate content after swimming were determined to evaluate the anti-fatigue effect of the beverage. Suppression of delayed type hypersensitivity and carbon clearance enhancement were conducted to determine the immune-enhancing function. After adult mice were fed with a high-fat diet and simultaneously administered orally with different dosages of the fortified beverage, serum total cholesterol(TC) and triglyceride(TG) concentrations were detected to evaluate the auxiliary lipid-lowering effect in mice. After adult hyperglycemic mice were orally administered with different dosages of the beverage, blood glucose concentration was detected to evaluate the auxiliary hypoglycemic effect in vivo. Results: In anti-fatigue tests, the weight-loaded forced swimming time of mice was significantly increased, while liver glycogen level was significantly elevated and the area under the curve of blood lactate was significantly reduced in the treatment group when compared with the blank group. The swelling degree of ears was significantly reduced, and the clearance index and the phagocytosis index were significantly increased, as indicated by the immune-enhancing effects of the beverage. Its auxiliary lipid-lowering effect indicated serum TC and TG levels were significantly reduced and the body weight of mice was lower than that of the control. As for its auxiliary hypoglycemic activity, blood glucose concentration was significantly decreased. In addition, all these biological activities were dosage dependent. The efficacy of the fortified beverage was better than that of Cordyceps militaris polysaccharides and apple cider vinegar separately. Conclusion: Apple cider vinegar fortified with Cordyceps militaris polysaccharides has anti-fatigue, immune-enhancing, auxiliary lipid-lowering and auxiliary hypoglycemic effects in mice." @default.
- W3140428462 created "2021-04-13" @default.
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- W3140428462 date "2014-01-01" @default.
- W3140428462 modified "2023-09-28" @default.
- W3140428462 title "Healthcare Functions of Apple Cider Vinegar Fortified with Cordyceps militaris Polysaccharides" @default.
- W3140428462 hasPublicationYear "2014" @default.
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