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- W3140459713 abstract "瞄准：与胰腺的癌症特征学习胰十二指肠的 homeobox-1 的关联包括病理学的分级， TNM 分级，瘤转移和肿瘤房间增长。方法：反向的 transcriptase 聚合酶链反应(RT-PCR ) 被用来在胰腺的癌症织物和正常胰腺的织物检测 PDX-1 mRNA 表示。PDX-1 蛋白质的表示被西方的污点和免疫组织化学测量。Immunohistochemistry 也被用来检测增生的房间原子抗原(PCNA ) 。有胰腺的癌症特征的 PDX-1 的关联包括病理学的分级，分级的 TNM，瘤转移和肿瘤房间增长，被使用 c2 分析测试。结果：Immunohistochemistry 证明 41.1% 胰腺的癌症为 PDX-1 表示是积极的，但是除了小岛的正常胰腺的组织没显示出为 PDX-1 染色。在里面与 imunohistochemistry 的结果一致，西方的污点证明 37.5% 胰腺的癌症为 PDX-1 是积极的。RT-PCR 证明那 PDX-1 表情比正常胰腺的纸巾在胰腺的癌症纸巾是显著地更高的(2-3.56 +/- 0.35 对 2-8.76 +/- 0.14， P < 0.01 ) 。淋巴节点转移(P < 0.01 ) ，分级的 TNM (P < 0.05 ) ，病理学的分级(P < 0.05 ) 并且肿瘤房间增长(P < 0.01 ) 显著地与 PDX-1 表示层次被相关。结论：PDX-1 在胰腺的癌症被重新表示，并且 PDX-1-positive 胰腺的癌症房间与 PDX-1-negative 房间相比显示出更恶意的潜力。因此， PDX-1-positive 房间可以是肿瘤干细胞， PDX-1 可以充当胰腺的癌症干细胞的交替的表面标记。" @default.
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- W3140459713 date "2007-01-01" @default.
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- W3140459713 title "Pancreas duodenal homeobox-1 expression and significance in pancreatic cancer" @default.
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