Matches in SemOpenAlex for { <https://semopenalex.org/work/W3140563784> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W3140563784 abstract "The present study was undertaken to evaluate the effect of somatostatin (SS) receptor,a brain-gut peptide receptor which is capable of inhibiting central neurons, on the pathogenesis of hepatic encephalopathy (HE).By means of radioligand binding assay, SS receptors in crude synaptosomal membrane of rat brains were investigated in a rat model of HE induced by partial hepatectomy following carbon tetrachloride intoxication and in controls. Binding to SS receptor was studied using125 I-SS as radiolgand Scatchard analysis of binding data was linear, yielding a dissociation constant (Kd) of 3.99 ±0.22 nmol/L and a maximal binding capacity (Bmax) of 238± 14.2 fmol/mg of protein in HE rats.Only increased Bmax values were observed (P 0.005),while the Kd values were statistically unchanged (P0.50),in HE rats as compared with those in controls.The results suggest that the changes of SS receptors in brains play a significant role in the pathogenesis of HE.The mechanism of HE induced by the alterations of SS receptors in the brains was discussed in this paper." @default.
- W3140563784 created "2021-04-13" @default.
- W3140563784 creator A5085810087 @default.
- W3140563784 date "1994-01-01" @default.
- W3140563784 modified "2023-09-24" @default.
- W3140563784 title "An Experimental Study on Somatostatin Receptors in the Brains of Hepatic Encephalopathy Rats" @default.
- W3140563784 hasPublicationYear "1994" @default.
- W3140563784 type Work @default.
- W3140563784 sameAs 3140563784 @default.
- W3140563784 citedByCount "0" @default.
- W3140563784 crossrefType "journal-article" @default.
- W3140563784 hasAuthorship W3140563784A5085810087 @default.
- W3140563784 hasConcept C126322002 @default.
- W3140563784 hasConcept C134018914 @default.
- W3140563784 hasConcept C170493617 @default.
- W3140563784 hasConcept C185592680 @default.
- W3140563784 hasConcept C2776297358 @default.
- W3140563784 hasConcept C2777214474 @default.
- W3140563784 hasConcept C2780325230 @default.
- W3140563784 hasConcept C2780942790 @default.
- W3140563784 hasConcept C67847695 @default.
- W3140563784 hasConcept C71924100 @default.
- W3140563784 hasConcept C74998103 @default.
- W3140563784 hasConcept C80115893 @default.
- W3140563784 hasConcept C86803240 @default.
- W3140563784 hasConceptScore W3140563784C126322002 @default.
- W3140563784 hasConceptScore W3140563784C134018914 @default.
- W3140563784 hasConceptScore W3140563784C170493617 @default.
- W3140563784 hasConceptScore W3140563784C185592680 @default.
- W3140563784 hasConceptScore W3140563784C2776297358 @default.
- W3140563784 hasConceptScore W3140563784C2777214474 @default.
- W3140563784 hasConceptScore W3140563784C2780325230 @default.
- W3140563784 hasConceptScore W3140563784C2780942790 @default.
- W3140563784 hasConceptScore W3140563784C67847695 @default.
- W3140563784 hasConceptScore W3140563784C71924100 @default.
- W3140563784 hasConceptScore W3140563784C74998103 @default.
- W3140563784 hasConceptScore W3140563784C80115893 @default.
- W3140563784 hasConceptScore W3140563784C86803240 @default.
- W3140563784 hasLocation W31405637841 @default.
- W3140563784 hasOpenAccess W3140563784 @default.
- W3140563784 hasPrimaryLocation W31405637841 @default.
- W3140563784 hasRelatedWork W1485888459 @default.
- W3140563784 hasRelatedWork W1968964955 @default.
- W3140563784 hasRelatedWork W1972700598 @default.
- W3140563784 hasRelatedWork W1975871300 @default.
- W3140563784 hasRelatedWork W1995131594 @default.
- W3140563784 hasRelatedWork W2002443646 @default.
- W3140563784 hasRelatedWork W2026643682 @default.
- W3140563784 hasRelatedWork W2034542433 @default.
- W3140563784 hasRelatedWork W2047613619 @default.
- W3140563784 hasRelatedWork W2054497345 @default.
- W3140563784 hasRelatedWork W2075238796 @default.
- W3140563784 hasRelatedWork W2080996208 @default.
- W3140563784 hasRelatedWork W2084071053 @default.
- W3140563784 hasRelatedWork W2091172269 @default.
- W3140563784 hasRelatedWork W2093558754 @default.
- W3140563784 hasRelatedWork W2093699488 @default.
- W3140563784 hasRelatedWork W2153896720 @default.
- W3140563784 hasRelatedWork W2171684241 @default.
- W3140563784 hasRelatedWork W2276888165 @default.
- W3140563784 hasRelatedWork W2994526672 @default.
- W3140563784 isParatext "false" @default.
- W3140563784 isRetracted "false" @default.
- W3140563784 magId "3140563784" @default.
- W3140563784 workType "article" @default.