Matches in SemOpenAlex for { <https://semopenalex.org/work/W3140667036> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3140667036 endingPage "98" @default.
- W3140667036 startingPage "90" @default.
- W3140667036 abstract "最近的证据建议承认多糖症与 intracerebral 出血(ICH ) 在幸存和病人的功能的结果上有有害效果。在这研究，我们首先由 50% 葡萄糖(6 mL/kg ) 的 intraperitoneal 注射在男成年 Sprague-Dawley 老鼠导致了尖锐多糖症，并且由交付自体同源的整个血或相应 normalglucose 血进恰好基础的 ganglia 此后创造了 ICH 模型。Twentyfour 小时以后，我们估计了神经病学的损害，评估了 hematoma 和大脑水内容，和调查 autophagy。我们发现神经病学的赤字分数，大脑水内容，和联系微导管的蛋白质的举起点亮 chain-3 (LC3 ) 和 beclin-1 蛋白质层次，并且减少在有正常葡萄糖的血的 ICH 以后的 SQSTM1/ p62 层次(没有多糖症) 。有高葡萄糖的血 hematoma 的 ICH 的尖锐多糖症与显著地增加的前肢使用不对称现象测试分数，大脑水内容和 SQSTM1/p62 蛋白质被联系在 LC3-II/LC3-I 和 beclin-1 蛋白质层次的比率的层次，和明显的减少。在另一方面，有 normalglucose 血 hematoma 的尖锐多糖症和 ICH 仅仅稍微增加了神经病学的赤字分数和大脑水内容(P > 0.05 ) 。在结论， autophagy 小径在 ICH 以后被激活，并且有高葡萄糖的血的 hematoma 的尖锐多糖症加重神经病学的损害，并且在 hematoma 附近减少 autophagy。" @default.
- W3140667036 created "2021-04-13" @default.
- W3140667036 creator A5002348937 @default.
- W3140667036 creator A5003385581 @default.
- W3140667036 creator A5023884404 @default.
- W3140667036 creator A5025879011 @default.
- W3140667036 creator A5031774992 @default.
- W3140667036 creator A5032245741 @default.
- W3140667036 creator A5065168162 @default.
- W3140667036 creator A5077918908 @default.
- W3140667036 date "2014-01-01" @default.
- W3140667036 modified "2023-09-23" @default.
- W3140667036 title "Acute hyperglycemia together with hematoma of high-glucose blood exacerbates neurological injury in a rat model of intracerebral hemorrhage" @default.
- W3140667036 hasPublicationYear "2014" @default.
- W3140667036 type Work @default.
- W3140667036 sameAs 3140667036 @default.
- W3140667036 citedByCount "0" @default.
- W3140667036 crossrefType "journal-article" @default.
- W3140667036 hasAuthorship W3140667036A5002348937 @default.
- W3140667036 hasAuthorship W3140667036A5003385581 @default.
- W3140667036 hasAuthorship W3140667036A5023884404 @default.
- W3140667036 hasAuthorship W3140667036A5025879011 @default.
- W3140667036 hasAuthorship W3140667036A5031774992 @default.
- W3140667036 hasAuthorship W3140667036A5032245741 @default.
- W3140667036 hasAuthorship W3140667036A5065168162 @default.
- W3140667036 hasAuthorship W3140667036A5077918908 @default.
- W3140667036 hasConcept C141071460 @default.
- W3140667036 hasConcept C185592680 @default.
- W3140667036 hasConcept C190283241 @default.
- W3140667036 hasConcept C203522944 @default.
- W3140667036 hasConcept C2777094939 @default.
- W3140667036 hasConcept C2777736543 @default.
- W3140667036 hasConcept C2779662492 @default.
- W3140667036 hasConcept C3017656743 @default.
- W3140667036 hasConcept C42219234 @default.
- W3140667036 hasConcept C55493867 @default.
- W3140667036 hasConcept C71924100 @default.
- W3140667036 hasConceptScore W3140667036C141071460 @default.
- W3140667036 hasConceptScore W3140667036C185592680 @default.
- W3140667036 hasConceptScore W3140667036C190283241 @default.
- W3140667036 hasConceptScore W3140667036C203522944 @default.
- W3140667036 hasConceptScore W3140667036C2777094939 @default.
- W3140667036 hasConceptScore W3140667036C2777736543 @default.
- W3140667036 hasConceptScore W3140667036C2779662492 @default.
- W3140667036 hasConceptScore W3140667036C3017656743 @default.
- W3140667036 hasConceptScore W3140667036C42219234 @default.
- W3140667036 hasConceptScore W3140667036C55493867 @default.
- W3140667036 hasConceptScore W3140667036C71924100 @default.
- W3140667036 hasIssue "1" @default.
- W3140667036 hasLocation W31406670361 @default.
- W3140667036 hasOpenAccess W3140667036 @default.
- W3140667036 hasPrimaryLocation W31406670361 @default.
- W3140667036 hasRelatedWork W1545844367 @default.
- W3140667036 hasRelatedWork W1970582346 @default.
- W3140667036 hasRelatedWork W1973705413 @default.
- W3140667036 hasRelatedWork W1979781332 @default.
- W3140667036 hasRelatedWork W2003268526 @default.
- W3140667036 hasRelatedWork W2011527633 @default.
- W3140667036 hasRelatedWork W2017269577 @default.
- W3140667036 hasRelatedWork W2311009612 @default.
- W3140667036 hasRelatedWork W2384219443 @default.
- W3140667036 hasRelatedWork W2608301324 @default.
- W3140667036 hasRelatedWork W2675971453 @default.
- W3140667036 hasRelatedWork W2787534243 @default.
- W3140667036 hasRelatedWork W2946019283 @default.
- W3140667036 hasRelatedWork W2989919451 @default.
- W3140667036 hasRelatedWork W3137183489 @default.
- W3140667036 hasRelatedWork W3157055769 @default.
- W3140667036 hasRelatedWork W3187669646 @default.
- W3140667036 hasRelatedWork W3204202927 @default.
- W3140667036 hasRelatedWork W2730193201 @default.
- W3140667036 hasRelatedWork W3029356923 @default.
- W3140667036 isParatext "false" @default.
- W3140667036 isRetracted "false" @default.
- W3140667036 magId "3140667036" @default.
- W3140667036 workType "article" @default.