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- W3140771433 abstract "This study was purposed to investigate the safety and effectivity of haploidentical stem cell transplantation for chronic aplastic anemia( CAA) by using two kind of third part cells: umbilical cord derived mesenchymal stem cells( hUCMSC) and haploidentical umbilical cord blood cells. The patient is a girl of 12 year old with CAA for 11 years. The donor was her mother. Graft come from haploidentical hematopoietic bone marrow and peripheral blood mobilized with granulocyte clonystimulating factor( G-CSF). The human umbilical cord derived mesenchymal stem cells and the haploidentical umbilical cord blood cells were transfered as third pard of cell. The graft-versus-host disease( GVHD) was prevented with CsA,MTX,ATG, CD25 and mycophenolate mofetial. The results indicated that the infused numbers of MNC and CD34+cells of donor were 7. 92 × 108/ kg and 3. 78 × 106/ kg,respectively. The numbers of neutrophils and platelets were over 0. 5 × 109/ L and 20 × 109/ L on days 12 and 14,respectively. On day 35 the chimeras accounted for 94%. No serious complications appeared up to now. In couclution,the preliminary results suggest that transplanta-tion of haploidentical hematopoietic stem cells combined with two kind of third part cells is safe and satisfactory." @default.
- W3140771433 created "2021-04-13" @default.
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- W3140771433 date "2013-01-01" @default.
- W3140771433 modified "2023-09-23" @default.
- W3140771433 title "Transplantation of Haploidentical-hematopoietic Stem Cells Combined with Two Kind of Third Part Cells for Chronic Aplastic Anemia: One Case Report" @default.
- W3140771433 hasPublicationYear "2013" @default.
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