FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3140881303> ?p ?o ?g. }

• W3140881303 abstract "BACKGROUND This study was conducted to compare and evaluate the efficacy and safety of prior intravenous dexmedetomidine with intravenous lignocaine as pre-treatment for prevention of propofol injection pain. METHODS In this prospective, randomised and double blinded clinical study, a total of 200 patients aged between 18 and 70 years of American Society of Anaesthesiologists (ASA) grade I or II posted for elective surgery under general anaesthesia utilising propofol as the inducing agent, were randomly allocated into two groups of 100 patients each, using computer generated random number tables. Group I received intravenous lignocaine 0.2 mg / Kg and group II received intravenous dexmedetomidine 0.5 mcg / Kg respectively prior to administration of propofol (2 mg / Kg) for induction during general anaesthesia. Pain during propofol administration was assessed for each patient using the McCririck and Hunter scale. Peri-operative haemodynamic changes and side effects were noted. Data was analysed using chi-square test and a P-value < 0.05 was considered to be statistically significant. RESULTS A total of 200 patients (100 patients in lignocaine group and 100 patients in dexmedetomidine group) were studied. Statistically significant (P < 0.05) diminution in pain score was discovered to be higher in group II (dexmedetomidine) as compared to group I (lignocaine). 80 % in the dexmedetomidine group had no pain compared to 62 % of the patients in the lignocaine group which is statistically significant. Dexmedetomidine also had a more remarkable effect on the heart rate (10 minutes after intubation) compared to lignocaine, with P = 0.054 which is statistically significant. CONCLUSIONS Intravenous dexmedetomidine is a superior pre-medication compared to intravenous lignocaine in the prevention of pain following propofol administration. It also has additional properties of sedation, analgesia, anxiolysis and sympatholytic action making it a better alternative for the anaesthesiologist and the patient. KEY WORDS Analgesia, Anxiolysis, Pre-Treatment, General Anaesthesia, Sedation, Sympatholytic Action" @default.
• W3140881303 created "2021-04-13" @default.
• W3140881303 creator A5010773088 @default.
• W3140881303 creator A5091645233 @default.
• W3140881303 date "2021-03-29" @default.
• W3140881303 modified "2023-09-26" @default.
• W3140881303 title "Comparison of Intravenous Lignocaine and Dexmedetomidine for Prevention of Propofol Injection Pain" @default.
• W3140881303 cites W1514084108 @default.
• W3140881303 cites W1967416443 @default.
• W3140881303 cites W1982728662 @default.
• W3140881303 cites W1983539493 @default.
• W3140881303 cites W1994339914 @default.
• W3140881303 cites W1996458302 @default.
• W3140881303 cites W2019954654 @default.
• W3140881303 cites W2026989438 @default.
• W3140881303 cites W2027540197 @default.
• W3140881303 cites W2032660180 @default.
• W3140881303 cites W2034557139 @default.
• W3140881303 cites W2035230043 @default.
• W3140881303 cites W2037882602 @default.
• W3140881303 cites W2042605819 @default.
• W3140881303 cites W2044911849 @default.
• W3140881303 cites W2047486276 @default.
• W3140881303 cites W2073827076 @default.
• W3140881303 cites W2088466911 @default.
• W3140881303 cites W2089232629 @default.
• W3140881303 cites W2095243495 @default.
• W3140881303 cites W2114496083 @default.
• W3140881303 cites W2131745075 @default.
• W3140881303 cites W2143926567 @default.
• W3140881303 cites W2151640235 @default.
• W3140881303 cites W2317713035 @default.
• W3140881303 cites W2400120214 @default.
• W3140881303 cites W2491995139 @default.
• W3140881303 cites W2951112459 @default.
• W3140881303 cites W3026377005 @default.
• W3140881303 cites W4241209760 @default.
• W3140881303 cites W4244667188 @default.
• W3140881303 cites W4249422015 @default.
• W3140881303 cites W4252165199 @default.
• W3140881303 cites W4253439486 @default.
• W3140881303 doi "https://doi.org/10.14260/jemds/2021/202" @default.
• W3140881303 hasPublicationYear "2021" @default.
• W3140881303 type Work @default.
• W3140881303 sameAs 3140881303 @default.
• W3140881303 citedByCount "0" @default.
• W3140881303 crossrefType "journal-article" @default.
• W3140881303 hasAuthorship W3140881303A5010773088 @default.
• W3140881303 hasAuthorship W3140881303A5091645233 @default.
• W3140881303 hasBestOaLocation W31408813031 @default.
• W3140881303 hasConcept C141071460 @default.
• W3140881303 hasConcept C2776277131 @default.
• W3140881303 hasConcept C2776814716 @default.
• W3140881303 hasConcept C2778716859 @default.
• W3140881303 hasConcept C2781302539 @default.
• W3140881303 hasConcept C42219234 @default.
• W3140881303 hasConcept C71924100 @default.
• W3140881303 hasConceptScore W3140881303C141071460 @default.
• W3140881303 hasConceptScore W3140881303C2776277131 @default.
• W3140881303 hasConceptScore W3140881303C2776814716 @default.
• W3140881303 hasConceptScore W3140881303C2778716859 @default.
• W3140881303 hasConceptScore W3140881303C2781302539 @default.
• W3140881303 hasConceptScore W3140881303C42219234 @default.
• W3140881303 hasConceptScore W3140881303C71924100 @default.
• W3140881303 hasLocation W31408813031 @default.
• W3140881303 hasOpenAccess W3140881303 @default.
• W3140881303 hasPrimaryLocation W31408813031 @default.
• W3140881303 hasRelatedWork W10117293 @default.
• W3140881303 hasRelatedWork W10319328 @default.
• W3140881303 hasRelatedWork W117880 @default.
• W3140881303 hasRelatedWork W14158314 @default.
• W3140881303 hasRelatedWork W1533961 @default.
• W3140881303 hasRelatedWork W1543251 @default.
• W3140881303 hasRelatedWork W19917362 @default.
• W3140881303 hasRelatedWork W20176225 @default.
• W3140881303 hasRelatedWork W20440739 @default.
• W3140881303 hasRelatedWork W3477231 @default.
• W3140881303 isParatext "false" @default.
• W3140881303 isRetracted "false" @default.
• W3140881303 magId "3140881303" @default.
• W3140881303 workType "article" @default.