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- W3140927130 abstract "Although many of the same pathogens that invade the juvenile or adult bovine also can produce disease in the neonatal calf, several physiological differences in the neonate make it much different than just a miniature cow. These physiological differences can alter the disposition of pharmaceutical agents (pharmacokinetics) in the neonate as well as alter the response of the neonate to a specific therapeutic agent (pharmacodynamics). After a brief overview of some terms used in pharmacokinetics, this paper will describe some physiological differences in neonates compared to adult cattle that are pertinent in drug disposition and response. Next, some specific examples of developmental changes in pharmacokinetics and pharmacodynamics will be described. Finally, some recommendations for drug therapy in neonatal calves will be suggested." @default.
- W3140927130 created "2021-04-13" @default.
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- W3140927130 date "1991-09-18" @default.
- W3140927130 modified "2023-10-05" @default.
- W3140927130 title "Pharmacology in Neonatal Calves" @default.
- W3140927130 cites W176734508 @default.
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- W3140927130 doi "https://doi.org/10.21423/aabppro19916722" @default.
- W3140927130 hasPublicationYear "1991" @default.
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