Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141008061> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W3141008061 abstract "Published data on the association between XRCC3 5 0 -UTR and IVS5-14 polymorphisms and breast cancer risk are inconclusive. In order to derive a more precise estimation of the relationship, a meta-analysis was performed. Crude ORs with 95% CIs were used to assess the strength of association between these polymorphisms and breast cancer risk. The pooled ORs were performed for codominant model, dominant model, and recessive model, respectively. A total of four studies were involved in the meta-analysis with 6,303 cases and 6,563 controls for XRCC3 5 0 -UTR polymorphism and with 6,270 cases and 6,682 controls for XRCC3 IVS5-14 polymorphism. For XRCC3 5 0 -UTR A/G polymorphism, significantly elevated breast cancer risk was associated with variant genotype when all studies were pooled into the meta-analysis (AG vs. AA: OR = 1.11, 95% CI = 1.03-1.19; dominant model: OR = 1.09, 95% CI = 1.01-1.17). For XRCC3 IVS5-14 A/G polymorphism, significantly decreased breast cancer risk was associated with variant genotype (GG vs. AA: OR = 0.86, 95% CI = 0.77-0.96). In conclusion, this meta-analysis suggests that the variant G allele of XRCC3 5 0 -UTR polymorphism is a low-penetrant risk factor for developing breast cancer, while the variant G allele of XRCC3 IVS5-14 polymorphism has a protective effect on breast cancer development." @default.
- W3141008061 created "2021-04-13" @default.
- W3141008061 creator A5009744121 @default.
- W3141008061 creator A5012267023 @default.
- W3141008061 creator A5059365838 @default.
- W3141008061 date "2010-01-01" @default.
- W3141008061 modified "2023-09-26" @default.
- W3141008061 title "XRCC3 5 0 -UTR and IVS5-14 polymorphisms and breast cancer susceptibility: a meta-analysis" @default.
- W3141008061 cites W2006249058 @default.
- W3141008061 cites W2020830322 @default.
- W3141008061 cites W2028203395 @default.
- W3141008061 cites W2035088189 @default.
- W3141008061 cites W2095761412 @default.
- W3141008061 cites W2106787323 @default.
- W3141008061 cites W2107328434 @default.
- W3141008061 cites W2128946284 @default.
- W3141008061 cites W2144845039 @default.
- W3141008061 cites W2150000105 @default.
- W3141008061 cites W2157823046 @default.
- W3141008061 cites W2158417496 @default.
- W3141008061 cites W2165172136 @default.
- W3141008061 cites W2315123323 @default.
- W3141008061 cites W2988844429 @default.
- W3141008061 hasPublicationYear "2010" @default.
- W3141008061 type Work @default.
- W3141008061 sameAs 3141008061 @default.
- W3141008061 citedByCount "0" @default.
- W3141008061 crossrefType "journal-article" @default.
- W3141008061 hasAuthorship W3141008061A5009744121 @default.
- W3141008061 hasAuthorship W3141008061A5012267023 @default.
- W3141008061 hasAuthorship W3141008061A5059365838 @default.
- W3141008061 hasConcept C104317684 @default.
- W3141008061 hasConcept C121608353 @default.
- W3141008061 hasConcept C126322002 @default.
- W3141008061 hasConcept C135763542 @default.
- W3141008061 hasConcept C143998085 @default.
- W3141008061 hasConcept C153209595 @default.
- W3141008061 hasConcept C180754005 @default.
- W3141008061 hasConcept C2779755913 @default.
- W3141008061 hasConcept C530470458 @default.
- W3141008061 hasConcept C54355233 @default.
- W3141008061 hasConcept C71924100 @default.
- W3141008061 hasConcept C86803240 @default.
- W3141008061 hasConcept C95190672 @default.
- W3141008061 hasConceptScore W3141008061C104317684 @default.
- W3141008061 hasConceptScore W3141008061C121608353 @default.
- W3141008061 hasConceptScore W3141008061C126322002 @default.
- W3141008061 hasConceptScore W3141008061C135763542 @default.
- W3141008061 hasConceptScore W3141008061C143998085 @default.
- W3141008061 hasConceptScore W3141008061C153209595 @default.
- W3141008061 hasConceptScore W3141008061C180754005 @default.
- W3141008061 hasConceptScore W3141008061C2779755913 @default.
- W3141008061 hasConceptScore W3141008061C530470458 @default.
- W3141008061 hasConceptScore W3141008061C54355233 @default.
- W3141008061 hasConceptScore W3141008061C71924100 @default.
- W3141008061 hasConceptScore W3141008061C86803240 @default.
- W3141008061 hasConceptScore W3141008061C95190672 @default.
- W3141008061 hasLocation W31410080611 @default.
- W3141008061 hasOpenAccess W3141008061 @default.
- W3141008061 hasPrimaryLocation W31410080611 @default.
- W3141008061 hasRelatedWork W2014688505 @default.
- W3141008061 hasRelatedWork W2039143344 @default.
- W3141008061 hasRelatedWork W2039516713 @default.
- W3141008061 hasRelatedWork W2054512303 @default.
- W3141008061 hasRelatedWork W2063314616 @default.
- W3141008061 hasRelatedWork W2086143001 @default.
- W3141008061 hasRelatedWork W2086437414 @default.
- W3141008061 hasRelatedWork W2097930250 @default.
- W3141008061 hasRelatedWork W2115032088 @default.
- W3141008061 hasRelatedWork W2118566039 @default.
- W3141008061 hasRelatedWork W2164416813 @default.
- W3141008061 hasRelatedWork W2296701010 @default.
- W3141008061 hasRelatedWork W2512094602 @default.
- W3141008061 hasRelatedWork W2734828847 @default.
- W3141008061 hasRelatedWork W3011957926 @default.
- W3141008061 hasRelatedWork W3023840647 @default.
- W3141008061 hasRelatedWork W3118393476 @default.
- W3141008061 hasRelatedWork W3130102056 @default.
- W3141008061 hasRelatedWork W3146766492 @default.
- W3141008061 hasRelatedWork W3150781978 @default.
- W3141008061 isParatext "false" @default.
- W3141008061 isRetracted "false" @default.
- W3141008061 magId "3141008061" @default.
- W3141008061 workType "article" @default.