Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141360884> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W3141360884 abstract "1-Oleoyl lysophosphatidic acid (LPA) enhanced binding of 125I-labeled fibronectin by cultured MG-63 osteosarcoma cells and human fibroblasts in monolayer cultures up to threefold over control levels. For osteosarcoma cells, LPA was minimally active at 0.1 ng/mL (0.2 nmol/L) and reached maximal activity at 10 ng/mL (20 nmol/L). Increased binding was evident within 10 minutes of treatment of cycloheximide-treated cells with LPA and was due to an increase in the number of fibronectin binding sites. LPA also increased the binding of a fragment containing the 70-kDa amino-terminal region of fibronectin that is primarily responsible for the reversible binding of fibronectin to matrix assembly sites on cell surfaces. Removal of LPA resulted in prompt return of fibronectin binding to baseline levels. These results indicate that LPA is an important enhancer of fibronectin-rich matrix deposition by cultured cells, and it may be the active component in serum and lipoprotein fractions that is responsible for enhancin..." @default.
- W3141360884 created "2021-04-13" @default.
- W3141360884 creator A5029126549 @default.
- W3141360884 creator A5042259135 @default.
- W3141360884 date "1993-01-01" @default.
- W3141360884 modified "2023-09-23" @default.
- W3141360884 title "Lysophosphatidic acid enhances fibronectin binding to adherent cells." @default.
- W3141360884 hasPublicationYear "1993" @default.
- W3141360884 type Work @default.
- W3141360884 sameAs 3141360884 @default.
- W3141360884 citedByCount "0" @default.
- W3141360884 crossrefType "journal-article" @default.
- W3141360884 hasAuthorship W3141360884A5029126549 @default.
- W3141360884 hasAuthorship W3141360884A5042259135 @default.
- W3141360884 hasConcept C107824862 @default.
- W3141360884 hasConcept C1491633281 @default.
- W3141360884 hasConcept C153911025 @default.
- W3141360884 hasConcept C170493617 @default.
- W3141360884 hasConcept C185592680 @default.
- W3141360884 hasConcept C2776661833 @default.
- W3141360884 hasConcept C2778128677 @default.
- W3141360884 hasConcept C3675279 @default.
- W3141360884 hasConcept C54355233 @default.
- W3141360884 hasConcept C55493867 @default.
- W3141360884 hasConcept C81885089 @default.
- W3141360884 hasConcept C86492073 @default.
- W3141360884 hasConcept C86803240 @default.
- W3141360884 hasConcept C95444343 @default.
- W3141360884 hasConceptScore W3141360884C107824862 @default.
- W3141360884 hasConceptScore W3141360884C1491633281 @default.
- W3141360884 hasConceptScore W3141360884C153911025 @default.
- W3141360884 hasConceptScore W3141360884C170493617 @default.
- W3141360884 hasConceptScore W3141360884C185592680 @default.
- W3141360884 hasConceptScore W3141360884C2776661833 @default.
- W3141360884 hasConceptScore W3141360884C2778128677 @default.
- W3141360884 hasConceptScore W3141360884C3675279 @default.
- W3141360884 hasConceptScore W3141360884C54355233 @default.
- W3141360884 hasConceptScore W3141360884C55493867 @default.
- W3141360884 hasConceptScore W3141360884C81885089 @default.
- W3141360884 hasConceptScore W3141360884C86492073 @default.
- W3141360884 hasConceptScore W3141360884C86803240 @default.
- W3141360884 hasConceptScore W3141360884C95444343 @default.
- W3141360884 hasLocation W31413608841 @default.
- W3141360884 hasOpenAccess W3141360884 @default.
- W3141360884 hasPrimaryLocation W31413608841 @default.
- W3141360884 hasRelatedWork W1507735847 @default.
- W3141360884 hasRelatedWork W1548710898 @default.
- W3141360884 hasRelatedWork W1584299780 @default.
- W3141360884 hasRelatedWork W1826692604 @default.
- W3141360884 hasRelatedWork W1919179089 @default.
- W3141360884 hasRelatedWork W1969770721 @default.
- W3141360884 hasRelatedWork W1994785222 @default.
- W3141360884 hasRelatedWork W1995795828 @default.
- W3141360884 hasRelatedWork W1996604216 @default.
- W3141360884 hasRelatedWork W1997400437 @default.
- W3141360884 hasRelatedWork W2005246591 @default.
- W3141360884 hasRelatedWork W2008980811 @default.
- W3141360884 hasRelatedWork W2030011981 @default.
- W3141360884 hasRelatedWork W2057056866 @default.
- W3141360884 hasRelatedWork W2082383806 @default.
- W3141360884 hasRelatedWork W2095014640 @default.
- W3141360884 hasRelatedWork W2132318925 @default.
- W3141360884 hasRelatedWork W2409489404 @default.
- W3141360884 hasRelatedWork W2413692563 @default.
- W3141360884 hasRelatedWork W2416153803 @default.
- W3141360884 isParatext "false" @default.
- W3141360884 isRetracted "false" @default.
- W3141360884 magId "3141360884" @default.
- W3141360884 workType "article" @default.