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- W3141495108 abstract "Herein, we describe a highly effective 1,8-conjugate-addition-mediated formal (3+3)-annulation of (aza)-para-quinone methides in situ generated from propargylic alcohols with 4-hydroxycoumarins and 1,3-dicarbonyl compounds under the catalysis of a Brønsted acid. This methodology affords efficient and practical access to synthetically important and highly functionalized pyranocoumarins and pyrans in excellent yields under mild conditions. Importantly, these products exhibit impressive inhibitory activity toward α-glucosidase." @default.
- W3141495108 created "2021-04-13" @default.
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- W3141495108 date "2021-04-06" @default.
- W3141495108 modified "2023-09-26" @default.
- W3141495108 title "Brønsted Acid-Catalyzed Formal (3+3)-Annulation of Propargylic (Aza)-<i>para</i>-Quinone Methides with 4-Hydroxycoumarins and 1,3-Dicarbonyl Compounds" @default.
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- W3141495108 doi "https://doi.org/10.1021/acs.joc.0c02844" @default.
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