FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141501143> ?p ?o ?g. }

• W3141501143 endingPage "7" @default.
• W3141501143 startingPage "1" @default.
• W3141501143 abstract "Helicobacter pylori pathogenicity and disease severity are determined by the tyrosine phosphorylation motifs of CagA protein. This study is aimed at detecting the presence of H. pylori and identifying the CagA tyrosine phosphorylation motifs in Ghanaian patients. Material and Methods. A total of 94 archival genomic DNA samples from gastric biopsies were used for the study, and H. pylori was detected by amplifying the 16S rRNA gene. The 3'-end variable region of the cagA gene was amplified, and the entire 3'-end was sequenced and translated into amino acids.H. pylori was detected in 53.2% (50/94) of the samples, and all the detected bacteria harboured the cagA gene. Two variants of the bacteria were identified based on the size of the amplified cagA gene: 207 bp and 285 bp. The 207 bp and 285 bp variants accounted for 74% and 22%, respectively, and 4% showed both fragments. Translated amino acid sequence of the cagA gene showed EPIYA-A, EPIYA-B, and EPIYA-C (ABC type) motifs, indicating the Western variant. The CagA protein C-terminal showed insertion of amino acids in the sequence flanking the EPIYA-A motif at the N-terminal and a complete deletion of the EPIYA-CC and EPIYA-CCC motifs together with the flanking sequences.H. pylori identified were Western variant (ABC type) with unique amino acid insertions, suggesting unique variants in Ghanaian patients. Further investigation is however required to understand the role of the molecular diversity of the variant in gastric disease outcome." @default.
• W3141501143 created "2021-04-13" @default.
• W3141501143 creator A5007184321 @default.
• W3141501143 creator A5026031023 @default.
• W3141501143 creator A5050877556 @default.
• W3141501143 creator A5052854242 @default.
• W3141501143 creator A5054975226 @default.
• W3141501143 creator A5061201022 @default.
• W3141501143 creator A5070522250 @default.
• W3141501143 date "2021-03-30" @default.
• W3141501143 modified "2023-09-25" @default.
• W3141501143 title "Helicobacter Pylori Variants with ABC-Type Tyrosine Phosphorylation Motif in Gastric Biopsies of Ghanaian Patients" @default.
• W3141501143 cites W1483774738 @default.
• W3141501143 cites W1514122220 @default.
• W3141501143 cites W1732962540 @default.
• W3141501143 cites W1756047451 @default.
• W3141501143 cites W1883668933 @default.
• W3141501143 cites W1964697014 @default.
• W3141501143 cites W1975116644 @default.
• W3141501143 cites W1978102284 @default.
• W3141501143 cites W1978165475 @default.
• W3141501143 cites W1984027402 @default.
• W3141501143 cites W1991464006 @default.
• W3141501143 cites W1998582997 @default.
• W3141501143 cites W1999417633 @default.
• W3141501143 cites W1999842625 @default.
• W3141501143 cites W2003186747 @default.
• W3141501143 cites W2018244151 @default.
• W3141501143 cites W2020782207 @default.
• W3141501143 cites W2034047068 @default.
• W3141501143 cites W2041924403 @default.
• W3141501143 cites W2052419566 @default.
• W3141501143 cites W2055667899 @default.
• W3141501143 cites W2064642615 @default.
• W3141501143 cites W2075163671 @default.
• W3141501143 cites W2092569336 @default.
• W3141501143 cites W2128697793 @default.
• W3141501143 cites W2162969038 @default.
• W3141501143 cites W2164393043 @default.
• W3141501143 cites W2175134890 @default.
• W3141501143 cites W2238681059 @default.
• W3141501143 cites W2248134792 @default.
• W3141501143 cites W2328585553 @default.
• W3141501143 cites W2399736935 @default.
• W3141501143 cites W2609752905 @default.
• W3141501143 cites W2609763100 @default.
• W3141501143 cites W2732686446 @default.
• W3141501143 cites W2754068978 @default.
• W3141501143 cites W2795995965 @default.
• W3141501143 cites W2800360574 @default.
• W3141501143 cites W2890162865 @default.
• W3141501143 doi "https://doi.org/10.1155/2021/6616059" @default.
• W3141501143 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8026283" @default.
• W3141501143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33860041" @default.
• W3141501143 hasPublicationYear "2021" @default.
• W3141501143 type Work @default.
• W3141501143 sameAs 3141501143 @default.
• W3141501143 citedByCount "2" @default.
• W3141501143 countsByYear W31415011432022 @default.
• W3141501143 crossrefType "journal-article" @default.
• W3141501143 hasAuthorship W3141501143A5007184321 @default.
• W3141501143 hasAuthorship W3141501143A5026031023 @default.
• W3141501143 hasAuthorship W3141501143A5050877556 @default.
• W3141501143 hasAuthorship W3141501143A5052854242 @default.
• W3141501143 hasAuthorship W3141501143A5054975226 @default.
• W3141501143 hasAuthorship W3141501143A5061201022 @default.
• W3141501143 hasAuthorship W3141501143A5070522250 @default.
• W3141501143 hasBestOaLocation W31415011431 @default.
• W3141501143 hasConcept C104317684 @default.
• W3141501143 hasConcept C153911025 @default.
• W3141501143 hasConcept C167625842 @default.
• W3141501143 hasConcept C2776165026 @default.
• W3141501143 hasConcept C2776409635 @default.
• W3141501143 hasConcept C2777553839 @default.
• W3141501143 hasConcept C2778204961 @default.
• W3141501143 hasConcept C515207424 @default.
• W3141501143 hasConcept C54355233 @default.
• W3141501143 hasConcept C55493867 @default.
• W3141501143 hasConcept C60987743 @default.
• W3141501143 hasConcept C86803240 @default.
• W3141501143 hasConceptScore W3141501143C104317684 @default.
• W3141501143 hasConceptScore W3141501143C153911025 @default.
• W3141501143 hasConceptScore W3141501143C167625842 @default.
• W3141501143 hasConceptScore W3141501143C2776165026 @default.
• W3141501143 hasConceptScore W3141501143C2776409635 @default.
• W3141501143 hasConceptScore W3141501143C2777553839 @default.
• W3141501143 hasConceptScore W3141501143C2778204961 @default.
• W3141501143 hasConceptScore W3141501143C515207424 @default.
• W3141501143 hasConceptScore W3141501143C54355233 @default.
• W3141501143 hasConceptScore W3141501143C55493867 @default.
• W3141501143 hasConceptScore W3141501143C60987743 @default.
• W3141501143 hasConceptScore W3141501143C86803240 @default.
• W3141501143 hasLocation W31415011431 @default.
• W3141501143 hasLocation W31415011432 @default.
• W3141501143 hasLocation W31415011433 @default.
• W3141501143 hasLocation W31415011434 @default.
• W3141501143 hasOpenAccess W3141501143 @default.
• W3141501143 hasPrimaryLocation W31415011431 @default.

• next