FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141502499> ?p ?o ?g. }

• W3141502499 endingPage "106747" @default.
• W3141502499 startingPage "106747" @default.
• W3141502499 abstract "This study was conducted to determine whether T cell populations are responsible for modulating placental development during gestation in cattle. It was hypothesized that CD4+CD25+ and γ/δ+ T cells modulate gene expression, based on mRNA transcript abundances, and promote proliferation and survival of trophoblast cells. Peripheral blood was collected from cows at 160 to 180 days of gestation and non-pregnant cows, T cell populations CD8+, CD4+, CD4+CD25+, CD24+CD25-, and γ/δ+ T cells were isolated, cultured for 48 h, and supernatant was collected. Placental samples were digested, and trophoblast cells were cultured for 24 h. Trophoblast cells were cultured with 50 μL of T cell-conditioned media and 50 μL of fresh culture media for an additional 48 h. Samples in control wells were treated with unconditioned media. Trophoblast cell proliferation, apoptosis, and mRNA transcript assays were conducted. There was no effect of T cell population on trophoblast apoptosis rate, proliferation, and relative mRNA transcript abundances. The T cell supernatant from pregnant and non-pregnant cows induced greater apoptosis rates in trophoblast cells than unconditioned media. Trophoblast cells proliferated less when treated with T cell supernatant from pregnant compared to unconditioned medium and non-pregnant cows. Treatment with the T cell supernatant from pregnant cows resulted in larger abundances of BMP5, IGF1R, PAG10, FGF2, RSPO3 and TMED2 and also a lesser abundance of FGF2 mRNA transcript than non-pregnant group and unconditioned media treatments. Supernatant from T cell derived from pregnant cows modulates trophoblast mRNA transcript abundances differently from T cell supernatant of non-pregnant cows." @default.
• W3141502499 created "2021-04-13" @default.
• W3141502499 creator A5002825880 @default.
• W3141502499 creator A5029400394 @default.
• W3141502499 creator A5047708249 @default.
• W3141502499 creator A5048171884 @default.
• W3141502499 creator A5059223838 @default.
• W3141502499 creator A5076477773 @default.
• W3141502499 date "2021-05-01" @default.
• W3141502499 modified "2023-10-17" @default.
• W3141502499 title "Lymphocyte soluble factors from pregnant cows modulate mRNA transcript abundances encoding for proteins associated with trophoblast growth and development" @default.
• W3141502499 cites W1599779773 @default.
• W3141502499 cites W1646439406 @default.
• W3141502499 cites W1971774838 @default.
• W3141502499 cites W1980057957 @default.
• W3141502499 cites W1983895762 @default.
• W3141502499 cites W1986046955 @default.
• W3141502499 cites W1995736467 @default.
• W3141502499 cites W2012070864 @default.
• W3141502499 cites W2014751423 @default.
• W3141502499 cites W2017041952 @default.
• W3141502499 cites W2018020394 @default.
• W3141502499 cites W2024224699 @default.
• W3141502499 cites W2024299100 @default.
• W3141502499 cites W2027772837 @default.
• W3141502499 cites W2029828963 @default.
• W3141502499 cites W2037547753 @default.
• W3141502499 cites W2052703349 @default.
• W3141502499 cites W2064081232 @default.
• W3141502499 cites W2067521643 @default.
• W3141502499 cites W2068754779 @default.
• W3141502499 cites W2076972535 @default.
• W3141502499 cites W2078645276 @default.
• W3141502499 cites W2082981899 @default.
• W3141502499 cites W2099703022 @default.
• W3141502499 cites W2126019211 @default.
• W3141502499 cites W2139802799 @default.
• W3141502499 cites W2146338099 @default.
• W3141502499 cites W2151273440 @default.
• W3141502499 cites W2156808865 @default.
• W3141502499 cites W2167303139 @default.
• W3141502499 cites W2168610830 @default.
• W3141502499 cites W2170288546 @default.
• W3141502499 cites W2172029080 @default.
• W3141502499 cites W2417406456 @default.
• W3141502499 cites W2465097793 @default.
• W3141502499 cites W2484510316 @default.
• W3141502499 cites W2681112686 @default.
• W3141502499 cites W2784107870 @default.
• W3141502499 cites W2831607512 @default.
• W3141502499 cites W2891141422 @default.
• W3141502499 cites W2911599751 @default.
• W3141502499 cites W2980609152 @default.
• W3141502499 doi "https://doi.org/10.1016/j.anireprosci.2021.106747" @default.
• W3141502499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33838589" @default.
• W3141502499 hasPublicationYear "2021" @default.
• W3141502499 type Work @default.
• W3141502499 sameAs 3141502499 @default.
• W3141502499 citedByCount "1" @default.
• W3141502499 countsByYear W31415024992022 @default.
• W3141502499 crossrefType "journal-article" @default.
• W3141502499 hasAuthorship W3141502499A5002825880 @default.
• W3141502499 hasAuthorship W3141502499A5029400394 @default.
• W3141502499 hasAuthorship W3141502499A5047708249 @default.
• W3141502499 hasAuthorship W3141502499A5048171884 @default.
• W3141502499 hasAuthorship W3141502499A5059223838 @default.
• W3141502499 hasAuthorship W3141502499A5076477773 @default.
• W3141502499 hasBestOaLocation W31415024991 @default.
• W3141502499 hasConcept C104317684 @default.
• W3141502499 hasConcept C105580179 @default.
• W3141502499 hasConcept C1491633281 @default.
• W3141502499 hasConcept C153911025 @default.
• W3141502499 hasConcept C16685009 @default.
• W3141502499 hasConcept C172680121 @default.
• W3141502499 hasConcept C190283241 @default.
• W3141502499 hasConcept C203014093 @default.
• W3141502499 hasConcept C2776953305 @default.
• W3141502499 hasConcept C2777495146 @default.
• W3141502499 hasConcept C2779234561 @default.
• W3141502499 hasConcept C2908647359 @default.
• W3141502499 hasConcept C54355233 @default.
• W3141502499 hasConcept C55493867 @default.
• W3141502499 hasConcept C62112901 @default.
• W3141502499 hasConcept C71924100 @default.
• W3141502499 hasConcept C86803240 @default.
• W3141502499 hasConcept C99454951 @default.
• W3141502499 hasConceptScore W3141502499C104317684 @default.
• W3141502499 hasConceptScore W3141502499C105580179 @default.
• W3141502499 hasConceptScore W3141502499C1491633281 @default.
• W3141502499 hasConceptScore W3141502499C153911025 @default.
• W3141502499 hasConceptScore W3141502499C16685009 @default.
• W3141502499 hasConceptScore W3141502499C172680121 @default.
• W3141502499 hasConceptScore W3141502499C190283241 @default.
• W3141502499 hasConceptScore W3141502499C203014093 @default.
• W3141502499 hasConceptScore W3141502499C2776953305 @default.
• W3141502499 hasConceptScore W3141502499C2777495146 @default.
• W3141502499 hasConceptScore W3141502499C2779234561 @default.
• W3141502499 hasConceptScore W3141502499C2908647359 @default.

• next