Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141584265> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W3141584265 abstract "We have previously demonstrated that transient cerebral ischemia induces marked decreases in concentrations of cytoskeletal proteins and have suggested putative involvement of calpain in the decrease of microtubule-associated protein 2 (MAP2) content. We examine the effect of nilvadipine, a new calcium channel blocker, on protein degradation in gerbil brains after 5 minutes of bilateral carotid artery occlusion and compare this effect with those of nimodipine and nicardipine. By densitometric quantification of the electrophoretically separated soluble proteins, mean +/- SEM MAP2 content in the hippocampus (14.4 +/- 1.8 micrograms/mg protein) was depleted (5.4 +/- 0.5 micrograms/mg, p less than 0.01) 4 days after ischemia; this depletion was significantly inhibited by 1 or 10 mg nilvadipine/kg/day. MAP2 content was also depleted in vitro when normal nonischemic brain extract was incubated with calcium, but this degradation was not inhibited by the calcium channel blockers. Our results suggest that calcium ..." @default.
- W3141584265 created "2021-04-13" @default.
- W3141584265 creator A5026078866 @default.
- W3141584265 creator A5031372947 @default.
- W3141584265 creator A5063056214 @default.
- W3141584265 creator A5063107536 @default.
- W3141584265 creator A5067218939 @default.
- W3141584265 creator A5089975724 @default.
- W3141584265 date "1989-01-01" @default.
- W3141584265 modified "2023-09-26" @default.
- W3141584265 title "Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins." @default.
- W3141584265 hasPublicationYear "1989" @default.
- W3141584265 type Work @default.
- W3141584265 sameAs 3141584265 @default.
- W3141584265 citedByCount "0" @default.
- W3141584265 crossrefType "journal-article" @default.
- W3141584265 hasAuthorship W3141584265A5026078866 @default.
- W3141584265 hasAuthorship W3141584265A5031372947 @default.
- W3141584265 hasAuthorship W3141584265A5063056214 @default.
- W3141584265 hasAuthorship W3141584265A5063107536 @default.
- W3141584265 hasAuthorship W3141584265A5067218939 @default.
- W3141584265 hasAuthorship W3141584265A5089975724 @default.
- W3141584265 hasConcept C126322002 @default.
- W3141584265 hasConcept C134018914 @default.
- W3141584265 hasConcept C142669718 @default.
- W3141584265 hasConcept C1491633281 @default.
- W3141584265 hasConcept C181199279 @default.
- W3141584265 hasConcept C2777294900 @default.
- W3141584265 hasConcept C2778043224 @default.
- W3141584265 hasConcept C2778820722 @default.
- W3141584265 hasConcept C2780222073 @default.
- W3141584265 hasConcept C2780356492 @default.
- W3141584265 hasConcept C2992195973 @default.
- W3141584265 hasConcept C42219234 @default.
- W3141584265 hasConcept C519063684 @default.
- W3141584265 hasConcept C541997718 @default.
- W3141584265 hasConcept C55493867 @default.
- W3141584265 hasConcept C56928146 @default.
- W3141584265 hasConcept C71924100 @default.
- W3141584265 hasConcept C85520022 @default.
- W3141584265 hasConcept C86803240 @default.
- W3141584265 hasConcept C98274493 @default.
- W3141584265 hasConceptScore W3141584265C126322002 @default.
- W3141584265 hasConceptScore W3141584265C134018914 @default.
- W3141584265 hasConceptScore W3141584265C142669718 @default.
- W3141584265 hasConceptScore W3141584265C1491633281 @default.
- W3141584265 hasConceptScore W3141584265C181199279 @default.
- W3141584265 hasConceptScore W3141584265C2777294900 @default.
- W3141584265 hasConceptScore W3141584265C2778043224 @default.
- W3141584265 hasConceptScore W3141584265C2778820722 @default.
- W3141584265 hasConceptScore W3141584265C2780222073 @default.
- W3141584265 hasConceptScore W3141584265C2780356492 @default.
- W3141584265 hasConceptScore W3141584265C2992195973 @default.
- W3141584265 hasConceptScore W3141584265C42219234 @default.
- W3141584265 hasConceptScore W3141584265C519063684 @default.
- W3141584265 hasConceptScore W3141584265C541997718 @default.
- W3141584265 hasConceptScore W3141584265C55493867 @default.
- W3141584265 hasConceptScore W3141584265C56928146 @default.
- W3141584265 hasConceptScore W3141584265C71924100 @default.
- W3141584265 hasConceptScore W3141584265C85520022 @default.
- W3141584265 hasConceptScore W3141584265C86803240 @default.
- W3141584265 hasConceptScore W3141584265C98274493 @default.
- W3141584265 hasLocation W31415842651 @default.
- W3141584265 hasOpenAccess W3141584265 @default.
- W3141584265 hasPrimaryLocation W31415842651 @default.
- W3141584265 hasRelatedWork W2007253526 @default.
- W3141584265 hasRelatedWork W2014030276 @default.
- W3141584265 hasRelatedWork W2043170711 @default.
- W3141584265 hasRelatedWork W2054389865 @default.
- W3141584265 hasRelatedWork W2059906034 @default.
- W3141584265 hasRelatedWork W2061984361 @default.
- W3141584265 hasRelatedWork W2064627891 @default.
- W3141584265 hasRelatedWork W2076185213 @default.
- W3141584265 hasRelatedWork W2347747752 @default.
- W3141584265 hasRelatedWork W2352856215 @default.
- W3141584265 hasRelatedWork W2364182121 @default.
- W3141584265 hasRelatedWork W2364417270 @default.
- W3141584265 hasRelatedWork W2367059990 @default.
- W3141584265 hasRelatedWork W2372213171 @default.
- W3141584265 hasRelatedWork W2383766467 @default.
- W3141584265 hasRelatedWork W2392501922 @default.
- W3141584265 hasRelatedWork W3141245952 @default.
- W3141584265 hasRelatedWork W3149306593 @default.
- W3141584265 hasRelatedWork W3150345144 @default.
- W3141584265 hasRelatedWork W3151126253 @default.
- W3141584265 isParatext "false" @default.
- W3141584265 isRetracted "false" @default.
- W3141584265 magId "3141584265" @default.
- W3141584265 workType "article" @default.