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- W3141681505 abstract "Spectrophotometric determination of irreversible proton pump inhibitor Rabeprazole sodium has been developed, the procedure is based on the formation of 2:1 chelate of drug and metal in ethanol media to form an orange colour chelate having an absorption maximum at 455nm. The regression analysis of Beer’s law showed a good correlation in the concentration range of 10 - 60µg/ml of pure Rabeprazole with Iron (Fe+3). The limit of detection was 1.98µg/ml and limit of quantification was 6.59µg/ml. The optimum assay conditions were investigated and the recovery of the drug from their dosage forms was found to be 99.8 – 100.3%. Good values of precision were obtained, intraday R.S.D was 0.1567 and interday R.S.D was 0.1792." @default.
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- W3141681505 date "2010-04-05" @default.
- W3141681505 modified "2023-09-27" @default.
- W3141681505 title "Validation of Spectrophotometric determination of Rabeprazole using Ferric Chloride (FeCl3)" @default.
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