FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141723557> ?p ?o ?g. }

• W3141723557 abstract "Recent genome-wide association study has identified a genetic variant rs4973768, located in 3 0 -UTR of solute carrier family 4, sodium bicarbonate cotrans- porter, member 7 (SLC4A7), was associated with increased risk of breast cancer (BC). However, several following replication studies cannot yield consistent results. We thus conducted a hospital-based case-control study including 485 patients and 514 controls, combined a meta-analysis including 108,632 cases and 135,818 controls to explore the relationship between this variant and BC risk. Our case-control study showed that rs4973768 was signifi- cantly associated with increased BC risk with the odds ratio (OR) of 1.29 (95 % confidence interval (CI): 1.04-1.60) under the allelic model. In addition, the meta-analysis also indicated that the variant slightly increased the risk of BC with the pooled OR of the per-allele effect being 1.08 (95 % CI: 1.04-1.11) although with significant heteroge- neity between studies. Stratified analyses showed that ethnicity, sample size, and study design may explain part of the heterogeneity. Moreover, the bioinformatics analysis suggested that this variant may influence the transcriptional capacity of SLC4A7. In summary, our results showed that the SLC4A7 variant, rs4973768, is associated with risk of BC although the underlying biologic mechanism warrants further studies." @default.
• W3141723557 created "2021-04-13" @default.
• W3141723557 creator A5017223679 @default.
• W3141723557 creator A5079821289 @default.
• W3141723557 date "2012-01-01" @default.
• W3141723557 modified "2023-09-27" @default.
• W3141723557 title "The SLC4A7 variant rs4973768 is associated with breast cancer risk: evidence from a case-control study and a meta-analysis" @default.
• W3141723557 cites W1964435302 @default.
• W3141723557 cites W1977923363 @default.
• W3141723557 cites W1982228885 @default.
• W3141723557 cites W1991038903 @default.
• W3141723557 cites W1994664175 @default.
• W3141723557 cites W2001701937 @default.
• W3141723557 cites W2006423274 @default.
• W3141723557 cites W2030892908 @default.
• W3141723557 cites W2031567251 @default.
• W3141723557 cites W2031772624 @default.
• W3141723557 cites W2050185058 @default.
• W3141723557 cites W2056051244 @default.
• W3141723557 cites W2064041354 @default.
• W3141723557 cites W2065658468 @default.
• W3141723557 cites W2089415609 @default.
• W3141723557 cites W2091381884 @default.
• W3141723557 cites W2097901251 @default.
• W3141723557 cites W2103123188 @default.
• W3141723557 cites W2105146818 @default.
• W3141723557 cites W2106787323 @default.
• W3141723557 cites W2107328434 @default.
• W3141723557 cites W2107578540 @default.
• W3141723557 cites W2116092230 @default.
• W3141723557 cites W2125435699 @default.
• W3141723557 cites W2130982499 @default.
• W3141723557 cites W2131612454 @default.
• W3141723557 cites W2132055476 @default.
• W3141723557 cites W2133218898 @default.
• W3141723557 cites W2134922322 @default.
• W3141723557 cites W2138918060 @default.
• W3141723557 cites W2143908444 @default.
• W3141723557 cites W2144151059 @default.
• W3141723557 cites W2144287526 @default.
• W3141723557 cites W2150000105 @default.
• W3141723557 cites W2150924792 @default.
• W3141723557 cites W2152395868 @default.
• W3141723557 cites W2156911571 @default.
• W3141723557 cites W2157823046 @default.
• W3141723557 cites W2163056200 @default.
• W3141723557 cites W2167144418 @default.
• W3141723557 cites W2168568597 @default.
• W3141723557 cites W2171221471 @default.
• W3141723557 hasPublicationYear "2012" @default.
• W3141723557 type Work @default.
• W3141723557 sameAs 3141723557 @default.
• W3141723557 citedByCount "0" @default.
• W3141723557 crossrefType "journal-article" @default.
• W3141723557 hasAuthorship W3141723557A5017223679 @default.
• W3141723557 hasAuthorship W3141723557A5079821289 @default.
• W3141723557 hasConcept C104317684 @default.
• W3141723557 hasConcept C106208931 @default.
• W3141723557 hasConcept C121608353 @default.
• W3141723557 hasConcept C126322002 @default.
• W3141723557 hasConcept C135763542 @default.
• W3141723557 hasConcept C143998085 @default.
• W3141723557 hasConcept C146304588 @default.
• W3141723557 hasConcept C153209595 @default.
• W3141723557 hasConcept C156957248 @default.
• W3141723557 hasConcept C180754005 @default.
• W3141723557 hasConcept C186413461 @default.
• W3141723557 hasConcept C2992519594 @default.
• W3141723557 hasConcept C44249647 @default.
• W3141723557 hasConcept C530470458 @default.
• W3141723557 hasConcept C54355233 @default.
• W3141723557 hasConcept C60644358 @default.
• W3141723557 hasConcept C71924100 @default.
• W3141723557 hasConcept C86803240 @default.
• W3141723557 hasConcept C95190672 @default.
• W3141723557 hasConceptScore W3141723557C104317684 @default.
• W3141723557 hasConceptScore W3141723557C106208931 @default.
• W3141723557 hasConceptScore W3141723557C121608353 @default.
• W3141723557 hasConceptScore W3141723557C126322002 @default.
• W3141723557 hasConceptScore W3141723557C135763542 @default.
• W3141723557 hasConceptScore W3141723557C143998085 @default.
• W3141723557 hasConceptScore W3141723557C146304588 @default.
• W3141723557 hasConceptScore W3141723557C153209595 @default.
• W3141723557 hasConceptScore W3141723557C156957248 @default.
• W3141723557 hasConceptScore W3141723557C180754005 @default.
• W3141723557 hasConceptScore W3141723557C186413461 @default.
• W3141723557 hasConceptScore W3141723557C2992519594 @default.
• W3141723557 hasConceptScore W3141723557C44249647 @default.
• W3141723557 hasConceptScore W3141723557C530470458 @default.
• W3141723557 hasConceptScore W3141723557C54355233 @default.
• W3141723557 hasConceptScore W3141723557C60644358 @default.
• W3141723557 hasConceptScore W3141723557C71924100 @default.
• W3141723557 hasConceptScore W3141723557C86803240 @default.
• W3141723557 hasConceptScore W3141723557C95190672 @default.
• W3141723557 hasLocation W31417235571 @default.
• W3141723557 hasOpenAccess W3141723557 @default.
• W3141723557 hasPrimaryLocation W31417235571 @default.
• W3141723557 hasRelatedWork W1997119391 @default.
• W3141723557 hasRelatedWork W2007849699 @default.
• W3141723557 hasRelatedWork W2030819548 @default.

• next