Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141848329> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W3141848329 abstract "Objective To study whether Lycium barbarum glycopeptide 3 (LBGP3) affects T cell apoptosis in aged mice. Methods LBGP3 was purified with DEAE cellulose and Sephadex columns. Apoptotic sub-G1 peak was detected by flow cytometry and DNA ladder was resolved by agarose gel electrophoresis. Levels of IFN-γ and IL-10 were measured with specific kits and mRNA expression was detected by RT-PCR. Apoptosis-related proteins of FLIP, FasL, and Bcl-2 were determined by Western blotting. Results LBGP3 was purified from Fructus Lycii water extracts and identified as a 41 kD glycopeptide. Treatment with 200 μg/mL LBGP3 increased the apoptotic rate of T cells from aged mice and showed a similar DNA ladder pattern to that in young T cells. The reversal of apoptotic resistance was involved in down-regulating the expression of Bcl-2 and FLIP, and up-regulating the expression of FasL. Conclusion Lycium barbarum glycopeptide 3 reverses apoptotic resistance of aged T cells by modulating the expression of apoptosis-related molecules." @default.
- W3141848329 created "2021-04-13" @default.
- W3141848329 creator A5030595942 @default.
- W3141848329 date "2008-01-01" @default.
- W3141848329 modified "2023-09-26" @default.
- W3141848329 title "Reversal of Apoptotic Resistance by Lycium barbarum Glycopeptide 3 in Aged T Cells" @default.
- W3141848329 hasPublicationYear "2008" @default.
- W3141848329 type Work @default.
- W3141848329 sameAs 3141848329 @default.
- W3141848329 citedByCount "0" @default.
- W3141848329 crossrefType "journal-article" @default.
- W3141848329 hasAuthorship W3141848329A5030595942 @default.
- W3141848329 hasConcept C104317684 @default.
- W3141848329 hasConcept C137610392 @default.
- W3141848329 hasConcept C142724271 @default.
- W3141848329 hasConcept C1491633281 @default.
- W3141848329 hasConcept C153911025 @default.
- W3141848329 hasConcept C163994747 @default.
- W3141848329 hasConcept C181199279 @default.
- W3141848329 hasConcept C185592680 @default.
- W3141848329 hasConcept C190283241 @default.
- W3141848329 hasConcept C203014093 @default.
- W3141848329 hasConcept C204787440 @default.
- W3141848329 hasConcept C2776108767 @default.
- W3141848329 hasConcept C2778271344 @default.
- W3141848329 hasConcept C31573885 @default.
- W3141848329 hasConcept C501593827 @default.
- W3141848329 hasConcept C552990157 @default.
- W3141848329 hasConcept C553184892 @default.
- W3141848329 hasConcept C55493867 @default.
- W3141848329 hasConcept C66008609 @default.
- W3141848329 hasConcept C71924100 @default.
- W3141848329 hasConcept C85265743 @default.
- W3141848329 hasConcept C86803240 @default.
- W3141848329 hasConceptScore W3141848329C104317684 @default.
- W3141848329 hasConceptScore W3141848329C137610392 @default.
- W3141848329 hasConceptScore W3141848329C142724271 @default.
- W3141848329 hasConceptScore W3141848329C1491633281 @default.
- W3141848329 hasConceptScore W3141848329C153911025 @default.
- W3141848329 hasConceptScore W3141848329C163994747 @default.
- W3141848329 hasConceptScore W3141848329C181199279 @default.
- W3141848329 hasConceptScore W3141848329C185592680 @default.
- W3141848329 hasConceptScore W3141848329C190283241 @default.
- W3141848329 hasConceptScore W3141848329C203014093 @default.
- W3141848329 hasConceptScore W3141848329C204787440 @default.
- W3141848329 hasConceptScore W3141848329C2776108767 @default.
- W3141848329 hasConceptScore W3141848329C2778271344 @default.
- W3141848329 hasConceptScore W3141848329C31573885 @default.
- W3141848329 hasConceptScore W3141848329C501593827 @default.
- W3141848329 hasConceptScore W3141848329C552990157 @default.
- W3141848329 hasConceptScore W3141848329C553184892 @default.
- W3141848329 hasConceptScore W3141848329C55493867 @default.
- W3141848329 hasConceptScore W3141848329C66008609 @default.
- W3141848329 hasConceptScore W3141848329C71924100 @default.
- W3141848329 hasConceptScore W3141848329C85265743 @default.
- W3141848329 hasConceptScore W3141848329C86803240 @default.
- W3141848329 hasLocation W31418483291 @default.
- W3141848329 hasOpenAccess W3141848329 @default.
- W3141848329 hasPrimaryLocation W31418483291 @default.
- W3141848329 hasRelatedWork W2166229755 @default.
- W3141848329 hasRelatedWork W2235306135 @default.
- W3141848329 hasRelatedWork W2351015295 @default.
- W3141848329 hasRelatedWork W2354528070 @default.
- W3141848329 hasRelatedWork W2363034077 @default.
- W3141848329 hasRelatedWork W2364632977 @default.
- W3141848329 hasRelatedWork W2368921792 @default.
- W3141848329 hasRelatedWork W2369435359 @default.
- W3141848329 hasRelatedWork W2372457703 @default.
- W3141848329 hasRelatedWork W2375356823 @default.
- W3141848329 hasRelatedWork W2375492179 @default.
- W3141848329 hasRelatedWork W2378558246 @default.
- W3141848329 hasRelatedWork W2388336150 @default.
- W3141848329 hasRelatedWork W2394284700 @default.
- W3141848329 hasRelatedWork W2463376573 @default.
- W3141848329 hasRelatedWork W2768032840 @default.
- W3141848329 hasRelatedWork W2991152612 @default.
- W3141848329 hasRelatedWork W3030089058 @default.
- W3141848329 hasRelatedWork W3032490582 @default.
- W3141848329 hasRelatedWork W3148335735 @default.
- W3141848329 isParatext "false" @default.
- W3141848329 isRetracted "false" @default.
- W3141848329 magId "3141848329" @default.
- W3141848329 workType "article" @default.