Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141969731> ?p ?o ?g. }
- W3141969731 endingPage "377" @default.
- W3141969731 startingPage "377" @default.
- W3141969731 abstract "We determined erythrocyte physiological and biochemical properties after the single and repeated administration of ultra-small superparamagnetic iron-oxide nanoparticles (USPIONs) in normotensive Wistar–Kyoto (WKY) and spontaneously hypertensive (SHR) rats. Polyethylene glycol-coated USPIONs (transmission electron microscope detected a mean size of ~30 nm and hydrodynamic size ~51 nm) were intravenously administered to rats either in one infusion at nominal dose 1 mg Fe/kg or in two infusions (administered with a difference of 24 h) at nominal dose 2 mg Fe/kg. Results showed that USPIONs did not deteriorate erythrocyte deformability, nitric oxide production, and osmotic resistance in both experimental settings. Both the single and repeated USPION administration elevated erythrocyte deformability in WKY. However, this effect was not present in SHR; deformability in USPION-treated SHR was significantly lower than in USPION-treated WKY. Nitric oxide production by erythrocytes was increased after a single USPION treatment in WKY, so it can be associated with improvement in erythrocyte deformability. Using biomagnetometry, we revealed significantly lower amounts of USPION-originated iron in erythrocytes in SHR compared with WKY. We found a much faster elimination of USPIONs from erythrocytes in hypertensive rats compared with the normotensive ones, which might be relevant for clinical practice in hypertensive patients undergoing clinical examination with the use of iron-oxide nanoparticles." @default.
- W3141969731 created "2021-04-13" @default.
- W3141969731 creator A5004673738 @default.
- W3141969731 creator A5005448874 @default.
- W3141969731 creator A5009072625 @default.
- W3141969731 creator A5031873820 @default.
- W3141969731 creator A5046590092 @default.
- W3141969731 creator A5059977458 @default.
- W3141969731 creator A5078525043 @default.
- W3141969731 creator A5084635537 @default.
- W3141969731 date "2021-04-02" @default.
- W3141969731 modified "2023-10-18" @default.
- W3141969731 title "Ultra-Small Superparamagnetic Iron-Oxide Nanoparticles Exert Different Effects on Erythrocytes in Normotensive and Hypertensive Rats" @default.
- W3141969731 cites W1580151493 @default.
- W3141969731 cites W1913092740 @default.
- W3141969731 cites W1966977447 @default.
- W3141969731 cites W1979273338 @default.
- W3141969731 cites W1979354267 @default.
- W3141969731 cites W1981622820 @default.
- W3141969731 cites W1991429693 @default.
- W3141969731 cites W2004410133 @default.
- W3141969731 cites W2006482913 @default.
- W3141969731 cites W2015950425 @default.
- W3141969731 cites W2022572312 @default.
- W3141969731 cites W2045080998 @default.
- W3141969731 cites W2048834534 @default.
- W3141969731 cites W2055665267 @default.
- W3141969731 cites W2066222724 @default.
- W3141969731 cites W2070550561 @default.
- W3141969731 cites W2090321557 @default.
- W3141969731 cites W2094854857 @default.
- W3141969731 cites W2096465912 @default.
- W3141969731 cites W2098922547 @default.
- W3141969731 cites W2106906710 @default.
- W3141969731 cites W2121221073 @default.
- W3141969731 cites W2135887696 @default.
- W3141969731 cites W2142248480 @default.
- W3141969731 cites W2164869629 @default.
- W3141969731 cites W2217267090 @default.
- W3141969731 cites W2233414233 @default.
- W3141969731 cites W2301011418 @default.
- W3141969731 cites W2528790823 @default.
- W3141969731 cites W2604606153 @default.
- W3141969731 cites W2766566369 @default.
- W3141969731 cites W2810413815 @default.
- W3141969731 cites W2890570039 @default.
- W3141969731 cites W2910814638 @default.
- W3141969731 cites W2935826158 @default.
- W3141969731 cites W2949515295 @default.
- W3141969731 cites W3002155983 @default.
- W3141969731 cites W3004216489 @default.
- W3141969731 cites W3010860489 @default.
- W3141969731 cites W3012646782 @default.
- W3141969731 cites W3040142808 @default.
- W3141969731 cites W3048581454 @default.
- W3141969731 cites W3091799046 @default.
- W3141969731 cites W3095011154 @default.
- W3141969731 doi "https://doi.org/10.3390/biomedicines9040377" @default.
- W3141969731 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8065606" @default.
- W3141969731 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33918438" @default.
- W3141969731 hasPublicationYear "2021" @default.
- W3141969731 type Work @default.
- W3141969731 sameAs 3141969731 @default.
- W3141969731 citedByCount "7" @default.
- W3141969731 countsByYear W31419697312021 @default.
- W3141969731 countsByYear W31419697312022 @default.
- W3141969731 countsByYear W31419697312023 @default.
- W3141969731 crossrefType "journal-article" @default.
- W3141969731 hasAuthorship W3141969731A5004673738 @default.
- W3141969731 hasAuthorship W3141969731A5005448874 @default.
- W3141969731 hasAuthorship W3141969731A5009072625 @default.
- W3141969731 hasAuthorship W3141969731A5031873820 @default.
- W3141969731 hasAuthorship W3141969731A5046590092 @default.
- W3141969731 hasAuthorship W3141969731A5059977458 @default.
- W3141969731 hasAuthorship W3141969731A5078525043 @default.
- W3141969731 hasAuthorship W3141969731A5084635537 @default.
- W3141969731 hasBestOaLocation W31419697311 @default.
- W3141969731 hasConcept C126322002 @default.
- W3141969731 hasConcept C134018914 @default.
- W3141969731 hasConcept C178790620 @default.
- W3141969731 hasConcept C185592680 @default.
- W3141969731 hasConcept C2776185378 @default.
- W3141969731 hasConcept C2776557347 @default.
- W3141969731 hasConcept C2776964284 @default.
- W3141969731 hasConcept C2777697756 @default.
- W3141969731 hasConcept C2778889443 @default.
- W3141969731 hasConcept C519581460 @default.
- W3141969731 hasConcept C55493867 @default.
- W3141969731 hasConcept C71924100 @default.
- W3141969731 hasConcept C98274493 @default.
- W3141969731 hasConceptScore W3141969731C126322002 @default.
- W3141969731 hasConceptScore W3141969731C134018914 @default.
- W3141969731 hasConceptScore W3141969731C178790620 @default.
- W3141969731 hasConceptScore W3141969731C185592680 @default.
- W3141969731 hasConceptScore W3141969731C2776185378 @default.
- W3141969731 hasConceptScore W3141969731C2776557347 @default.
- W3141969731 hasConceptScore W3141969731C2776964284 @default.
- W3141969731 hasConceptScore W3141969731C2777697756 @default.