Matches in SemOpenAlex for { <https://semopenalex.org/work/W3141991435> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W3141991435 abstract "Resistant variants of HSV-1 wt stain to ACV, CC, DHPG and PFAcan be selected after several passages in drug-containing cultures. The degree of resistanceof different variants varied and emerged at different times. The combination of antiviralagents can delay and even prevent the emergance of drug-resistant variants. At the sametime, the concentration, dose and, therefore, toxicity of the antiviral agents can also be re-duced. So, it is a feasible method for treating resistant HSV infections. Cross-sensitivitytests showed that ACV~r variants are resistant to ACV, DHPG and PFA, but sensitive toCC; PFA~r variants are sensitive to ACV, CC and DHPG; CC~r variants are sensitive toACV and DHPG, but resistant to PFA; DHPG~r variants are sensitive to ACV, CC andPFA, These results suggest that the study of cross-sensitivity of HSV strains in vitro pro- vide information which will aid the design of sultable therapy for drug-resistant HSV in-fections." @default.
- W3141991435 created "2021-04-13" @default.
- W3141991435 creator A5069306363 @default.
- W3141991435 date "1992-01-01" @default.
- W3141991435 modified "2023-09-27" @default.
- W3141991435 title "DEVELOPMENT OF RESISTANCE OF HERPES SIMPLES VIRUS TO ANTIVIRUS DRUGS IN VITRO" @default.
- W3141991435 hasPublicationYear "1992" @default.
- W3141991435 type Work @default.
- W3141991435 sameAs 3141991435 @default.
- W3141991435 citedByCount "0" @default.
- W3141991435 crossrefType "journal-article" @default.
- W3141991435 hasAuthorship W3141991435A5069306363 @default.
- W3141991435 hasConcept C114851261 @default.
- W3141991435 hasConcept C159047783 @default.
- W3141991435 hasConcept C178790620 @default.
- W3141991435 hasConcept C185592680 @default.
- W3141991435 hasConcept C202751555 @default.
- W3141991435 hasConcept C2522874641 @default.
- W3141991435 hasConcept C2780035454 @default.
- W3141991435 hasConcept C29730261 @default.
- W3141991435 hasConcept C36372059 @default.
- W3141991435 hasConcept C55493867 @default.
- W3141991435 hasConcept C86803240 @default.
- W3141991435 hasConcept C89423630 @default.
- W3141991435 hasConcept C98274493 @default.
- W3141991435 hasConceptScore W3141991435C114851261 @default.
- W3141991435 hasConceptScore W3141991435C159047783 @default.
- W3141991435 hasConceptScore W3141991435C178790620 @default.
- W3141991435 hasConceptScore W3141991435C185592680 @default.
- W3141991435 hasConceptScore W3141991435C202751555 @default.
- W3141991435 hasConceptScore W3141991435C2522874641 @default.
- W3141991435 hasConceptScore W3141991435C2780035454 @default.
- W3141991435 hasConceptScore W3141991435C29730261 @default.
- W3141991435 hasConceptScore W3141991435C36372059 @default.
- W3141991435 hasConceptScore W3141991435C55493867 @default.
- W3141991435 hasConceptScore W3141991435C86803240 @default.
- W3141991435 hasConceptScore W3141991435C89423630 @default.
- W3141991435 hasConceptScore W3141991435C98274493 @default.
- W3141991435 hasLocation W31419914351 @default.
- W3141991435 hasOpenAccess W3141991435 @default.
- W3141991435 hasPrimaryLocation W31419914351 @default.
- W3141991435 hasRelatedWork W1911415980 @default.
- W3141991435 hasRelatedWork W1966203536 @default.
- W3141991435 hasRelatedWork W1970349503 @default.
- W3141991435 hasRelatedWork W1983877828 @default.
- W3141991435 hasRelatedWork W2012325833 @default.
- W3141991435 hasRelatedWork W2045783031 @default.
- W3141991435 hasRelatedWork W2084375481 @default.
- W3141991435 hasRelatedWork W2158902719 @default.
- W3141991435 hasRelatedWork W2318096913 @default.
- W3141991435 hasRelatedWork W2354181080 @default.
- W3141991435 hasRelatedWork W2354668583 @default.
- W3141991435 hasRelatedWork W2367524645 @default.
- W3141991435 hasRelatedWork W2370166017 @default.
- W3141991435 hasRelatedWork W2375446098 @default.
- W3141991435 hasRelatedWork W2387679335 @default.
- W3141991435 hasRelatedWork W2472725189 @default.
- W3141991435 hasRelatedWork W2473885185 @default.
- W3141991435 hasRelatedWork W2794358738 @default.
- W3141991435 hasRelatedWork W2805270118 @default.
- W3141991435 hasRelatedWork W3140977388 @default.
- W3141991435 isParatext "false" @default.
- W3141991435 isRetracted "false" @default.
- W3141991435 magId "3141991435" @default.
- W3141991435 workType "article" @default.