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- W3142022708 abstract "瞄准:评估自然 diterpenoid 的效果, hypoest 氧化物(他) 在在老鼠的确定的结肠癌的生长上。方法:CT26.WT 老鼠结肠癌房间线被养并且膨胀在试管内。跟随扩大, BALB/c 老鼠被接种有可行肿瘤房间的 s.c。在肿瘤建立了并且发展到大约 80-90 mm3 以后,老鼠被口服在化疗上开始他, 5 氟尿嘧啶(5-FU ) 或联合。结果:他以前被给看了在 B16F1 肿瘤禁止黑瘤的生长的 antiangiogenic 在 C57BL/6 老鼠当模特儿。我们的结果在对待与的鼠标表明肿瘤的那吝啬的卷口头他作为一个单个代理人或在有 5-FU 的联合,显著地更小(> 60%) 比那些在车辆控制鼠标(471.2 mm3 对 1542.8 mm3, P < 0.01 ) 。在肿瘤负担的重要减小导致了显著吝啬的幸存时间(山区标准时间) 并且在对待的老鼠增加了生活跨度(ILS ) 。结论:他是一个有效化学疗法的代理人为的这些结果 indicate 在老鼠和那渲染表面的癌症他可以与 5-FU 独自或在联合被使用。" @default.
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- W3142022708 date "2007-01-01" @default.
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- W3142022708 title "Hypoestoxide inhibits tumor growth in the mouse CT26 colon tumor model" @default.
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