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- W3142104711 abstract "Autophagy 是一高度调整了并且 multistep 由此的生物过程房间在下面新陈代谢， proteotoxic，或另外的压力由 shuttling 移开不正常的细胞器或 misfolded/polyubiquitinated 蛋白质他们经由为降级称为 autophagosomes 到 lysosome 的专业化结构。尽管 autophagy 通常被认为是一个非选择的过程，积累的证据建议它能有选择地也降级特定的目标货物。这些选择目标包括蛋白质，线粒体，和平入侵细菌。autophagic 改编者的发现和描述，例如 p62/Sequestosome 1 (SQSTM1 ) 并且 BRCA1 基因 1 的邻居(NBR1 ) ，提供了机械学的卓见进选择 autophagy。这些受体都能为 ubiquitinated 底层的降级充当货物受体。这评论主要关于在调整选择 autophagy 起重要作用的关键受体蛋白质总结最新的调查结果。" @default.
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- W3142104711 date "2015-01-01" @default.
- W3142104711 modified "2023-09-27" @default.
- W3142104711 title "The receptor proteins： pivotal roles in selective autophagy" @default.
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