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- W3142158957 abstract "瞄准：构造 recombinant Lactococcus 乳酸作为对疟疾的口头的交货种痘。方法：变形体 yoelii 265-BY 的 MSP1 (MSP-1 (19 )) 的 C 终端 19-ku 碎片在 L 被表示。乳酸是并且 recombinant L。乳酸是予 BALB/c 和 C57BL/6 老鼠口头上地被以。在在 4 wk 以内的七间隔种痘以后，老鼠与 P 被质问。红细胞舞台的 yoelii 265-BY 寄生虫。recombinant L 的保护的功效。乳酸被评估。结果：分别地，在为 BALB/c 和 C57BL/6 鼠标的实验组的一般水准的山峰 parasitemias 是 0.8+/-0.4% 和 20.8+/-26.5% ，他们的控制组的那些分别地是 12.0+/-0.8% 和 60.8+/-9.6% 。任何一个都没在实验期间死于在试验性的组和控制组的 BALB/c 老鼠。然而，在控制组的所有 C57BL/6 鼠标在 23 d 和熬过很好的所有种牛痘的鼠标以内死了。结论：结果暗示 recombinant L 的潜力。乳酸作为对疟疾的口头的交货种痘。" @default.
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- W3142158957 date "2005-01-01" @default.
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- W3142158957 title "Oral vaccination of mice against rodent malaria with recombinant Lactococcus lactis expressing MSP-119" @default.
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