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- W3142233088 abstract "从 Streptomyces mycarofaciens 的二潜水艇簇，一个 midecamycin 制片人，被克隆并且部分定序。一个区域在中间的 polyketidesynthase (PKS ) 的 5 ′结束被定位基因并且包含了基因中间的 A， midB 和 midC。另外的区域在 PKS 基因的 3 ′ e nd 并且包含了 midK，半长裙和 midH。核苷酸顺序的分析表明这些基因编码 dTDP 葡萄糖合酶(中间的 A ) ， dTDP 葡萄糖 dehydratase (midB ) ，氨基转移酶(midC ) ，甲基转移酶(midK ) ，糖基转移酶(半长裙) 和助理基因(midH ) 。所有这些基因涉及 dTDP-D-mycaminose 的生合成， midecamycin 的 firstdeoxysugar，并且在斜斜地把 mycaminose 转移到 midecamycin 在 S.mycarofaciens 的锥。类似于在 S 的基因对 des Ⅷ / des Ⅶ。在 S 的 venezuelae 和 tylM Ⅲ / tylM Ⅱ。fradiae， midH 的产品可能作为半长裙蛋白质在 midecamycin 生合成为有效 glycosyltransfer 要求的辅助蛋白质工作。" @default.
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- W3142233088 date "2007-01-01" @default.
- W3142233088 modified "2023-09-24" @default.
- W3142233088 title "Cloning and Characterization of Genes Encoded in dTDP-D-mycaminose Biosynthetic Pathway from a Midecamycin-producing Strain,Streptomyces mycarofaciens" @default.
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