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- W3142360198 abstract "Aristolochia indica L. (Family Aristolochiaceae) has been used for the treatment of various ailments from the ancient time. The present study was conducted to investigate the effects of ingestion of the alcoholic extract of the p lant on liver and kidney functions in Wistar albino rats. Acute oral toxicity test was performed to determine the LD 50 , sub chronic toxicity was then carried out by the oral administration of different doses of the extract on daily basis to differen t group s of rats for 28 days. The animals were sacrificed and biochemical study was done. The acute oral toxicity result revealed that LD 50 of the alcoholic extract of A . indica was more than 7500mg/kg body weight but less than 10,000 mg/kg body weight. The resul t of sub chronic toxicity revealed that liver and kidney function of different groups receiving different doses of A. indica was affected as the SGOT, SGPT, total protein, urea nitrogen and creatinine was significantly elevated and uric acid level was sign ificantly declined as compared to control group." @default.
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- W3142360198 date "2011-01-01" @default.
- W3142360198 modified "2023-09-24" @default.
- W3142360198 title "TOXICITY STUDY OF ALCOHOLIC EXTRACT OF THE AERIAL PARTS OF ARISTOLOCHIA INDICA L." @default.
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