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- W3142877551 abstract "瞄准：为了是学习 N-acetylcysteine (NAC ) 的角色，在 rifampicin (RMP ) 的一个保护的代理人导致了小老鼠的氧化肝的损害。方法：肝的损害被为 3 wk 给 RMP 的 50 mg/kg 体重生产。NAC (100 mg/kg 体重) 的剂量 intraperitoneally 与 RMP 在联合被给。类脂化合物的分析与体重，肝重量和组织学的观察一起在肝每氧化，巯基层次，细胞色素 P450，超级氧化物歧化酶(草皮) ，过氧化氢酶，谷胱甘肽过氧化物酶，还原酶和转移酶被估计。结果：当抗氧化的酶被改变时， RMP 暴露在身体和肝重量导致了没有变化但是非，蛋白质巯基(GSH ) 地位很好被保存。细胞色素 P450 系统并且每类脂化合物的氧化被 RMP 暴露导致。部分保护在肝对导致 RMP 的变化与 NAC 被观察，它在草皮和过氧化氢酶酶层次每氧化和减小从类脂化合物的增加的预防被证实。结论：NAC 保护小老鼠免于导致 RMP 的氧化肝的损害。" @default.
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- W3142877551 date "2006-01-01" @default.
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- W3142877551 title "Role of N-acetylcysteine in rifampicin-induced hepatic injury of young rats" @default.
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