FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3142985220> ?p ?o ?g. }

• W3142985220 abstract "Background: Acute pain is a risk factor for developing postherpetic neuralgia (PHN), the most common complication of herpes zoster (HZ). Supplemental analgesics are frequently used in the treatment of acute herpetic pain. However, there are insufficient data regarding when to begin supplemental analgesics, and it is unknown whether the delayed use of supplemental analgesics increases the risk of PHN in high-risk patients. Objectives: This study aimed to evaluate the association between initial time of supplemental pain management and the risk of PHN in high-risk patients. Study Design: Retrospective study. Setting: The Department of Anesthesiology and Pain Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine. Methods: We performed a retrospective study between May 13, 2017 and August 8, 2018 in our clinic. Multivariable logistic regression analysis was conducted to examine the independent factors associated with PHN. Supplemental pain management was defined as any use of opioids, tricyclic antidepressants, or nerve blocks. A subgroup analysis was conducted in patients who received supplemental pain management within the first 30 days of onset. According to the initial time of supplemental pain management, patients were divided into 2 groups: the early treatment group (≤ 14 days), and the late treatment group (> 14 days). The clinical outcomes in these 2 groups was compared for propensity score (PS) matching. Results: A total of 134 patients with HZ aged 50 years or older with moderate to severe pain were enrolled in this study. The delayed initiation of supplemental pain management (> 14 days) (odds ratio, 4.11; 95% confidence interval, 1.69-9.92; P = 0.002) and severity of rash (odds ratio, 2.93; 95% confidence interval, 1.22-7.01; P = 0.016) were independent factors associated with PHN. In the subgroup analysis, after PS matching, there were no significant differences in the baseline clinical parameters between the early and late treatment groups. The incidence of PHN was significantly lower in the early treatment group than the late treatment group (36. 4% vs. 72.7%; P = 0.015). Reduction in pain was also greater in the early treatment group. Limitations: The findings identified in the present study are specific to the patients who were relatively older and with moderate to severe pain. It is impossible to determine from our study whether younger individuals and individuals with mild acute pain will benefit from early supplemental treatments. Furthermore, because of the retrospective nature of the study, there may be some confounders that could not be controlled. Further prospective studies with larger sample sizes and longer follow-up periods are needed. Conclusions: The early use of supplemental pain management may decrease the risk of PHN. It might therefore be beneficial to consider administering supplemental pain management earlier in older patients with moderate to severe acute herpetic pain. Key words: Herpes zoster, postherpetic neuralgia, analgesia, opioid, nerve block, tricyclic antidepressant" @default.
• W3142985220 created "2021-04-13" @default.
• W3142985220 creator A5012845876 @default.
• W3142985220 date "2020-01-14" @default.
• W3142985220 modified "2023-09-29" @default.
• W3142985220 title "Delayed Initiation of Supplemental Pain Management is Associated with Postherpetic Neuralgia: A Retrospective Study" @default.
• W3142985220 doi "https://doi.org/10.36076/ppj.2020/23/65" @default.
• W3142985220 hasPublicationYear "2020" @default.
• W3142985220 type Work @default.
• W3142985220 sameAs 3142985220 @default.
• W3142985220 citedByCount "0" @default.
• W3142985220 crossrefType "journal-article" @default.
• W3142985220 hasAuthorship W3142985220A5012845876 @default.
• W3142985220 hasConcept C126322002 @default.
• W3142985220 hasConcept C156957248 @default.
• W3142985220 hasConcept C167135981 @default.
• W3142985220 hasConcept C17923572 @default.
• W3142985220 hasConcept C2777107010 @default.
• W3142985220 hasConcept C2778866549 @default.
• W3142985220 hasConcept C2779526319 @default.
• W3142985220 hasConcept C2780820201 @default.
• W3142985220 hasConcept C2991975920 @default.
• W3142985220 hasConcept C42219234 @default.
• W3142985220 hasConcept C44249647 @default.
• W3142985220 hasConcept C71924100 @default.
• W3142985220 hasConceptScore W3142985220C126322002 @default.
• W3142985220 hasConceptScore W3142985220C156957248 @default.
• W3142985220 hasConceptScore W3142985220C167135981 @default.
• W3142985220 hasConceptScore W3142985220C17923572 @default.
• W3142985220 hasConceptScore W3142985220C2777107010 @default.
• W3142985220 hasConceptScore W3142985220C2778866549 @default.
• W3142985220 hasConceptScore W3142985220C2779526319 @default.
• W3142985220 hasConceptScore W3142985220C2780820201 @default.
• W3142985220 hasConceptScore W3142985220C2991975920 @default.
• W3142985220 hasConceptScore W3142985220C42219234 @default.
• W3142985220 hasConceptScore W3142985220C44249647 @default.
• W3142985220 hasConceptScore W3142985220C71924100 @default.
• W3142985220 hasLocation W31429852201 @default.
• W3142985220 hasOpenAccess W3142985220 @default.
• W3142985220 hasPrimaryLocation W31429852201 @default.
• W3142985220 hasRelatedWork W12404636 @default.
• W3142985220 hasRelatedWork W16787927 @default.
• W3142985220 hasRelatedWork W1698439 @default.
• W3142985220 hasRelatedWork W19667460 @default.
• W3142985220 hasRelatedWork W21288624 @default.
• W3142985220 hasRelatedWork W2259309 @default.
• W3142985220 hasRelatedWork W3937823 @default.
• W3142985220 hasRelatedWork W398036 @default.
• W3142985220 hasRelatedWork W8686003 @default.
• W3142985220 hasRelatedWork W4897599 @default.
• W3142985220 isParatext "false" @default.
• W3142985220 isRetracted "false" @default.
• W3142985220 magId "3142985220" @default.
• W3142985220 workType "article" @default.